Web evaluation of maceration length period on antioxidant potency of Sonneratia caseolaris leaf

¹ Marine Science Department, Fisheries and Marine Science Faculty of Brawijaya University, 65145, Indonesia
² Marine Resources Exploration and Management (MEXMA) Research Group, Brawijaya University, 65245, Indonesia
³ Pharmacy Academy, Putra Indonesia Foundation, 65126, Indonesia
⁴ Sekolah Tinggi Ilmu Perikanan (Fisheries Science College), 65141, Indonesia

^* Corresponding author: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Diabetic and cancer, as an examples of degenerative diseases in human may arise as consequences of free radicals, i.e. highly reactive molecules. The reactiveness of free radicals can be constrained by a substance, known as antioxidant. Mangroves that inhabitant of highly dynamic waters of estuary is likely have defend activity by produce some substances those known as bioactive compounds that may have potency of antioxidant. The quality and quantity of bioactive compounds may affected by extraction method. This study aims to evaluate antioxidant potency of Sonneratia caseolaris leaf with three diferent length time (24, 48 and 72 hours) of maceration by applying of DPPD (1,1-diphenyl-β-picryl hydrazyl) method. Result based on 50% of inhibition concentration (IC₅₀) value suggest that the best maceration time is 24 hours (IC₅₀ was 6.35 ppm), following by 72 and 48 hours (IC₅₀ were 11.5 and 17.4 ppm, respectively). In addition, overall of different maceration time show IC value lowe than 50 ppm, indicate that Sonneatia caseolaris leaf have very strong potential of antioxidant activity.