Biopolymeric materials with Moringa oleifera encapsulated essential oils, an innovative alternative to soft tissue wounds regeneration

Stefan cel Mare University of Suceava, 720229, Romania

^* Corresponding author: roxana.puscaselu@usm.ro

Abstract

Nowadays, the focus on developing materials with superior properties to those already known is of great interest. Biopolymers have demonstrated excellent properties and, due to their renewability, non-toxicity, non-allergenicity, and non-immunogenic nature, have become increasingly used in medical applications. Moreover, because of their ability to form a complex matrix, they allow for the prolonged and controlled release of encapsulated substances. This study aimed to develop wound dressings made from sodium alginate and Moringa oleifera essential oil, a plant known since ancient times for its exceptional regenerative properties. To prevent the degradation of the essential oil, it was entrapped in sodium alginate-based capsules. Tested for physicochemical, mechanical, solubility, and microbiological evaluation, the materials are suitable for use as dressings for mild, superficial wounds. Future research involves testing on cell lines and in vitro blood coagulation tests.