Study and characterisation of the alteration and devitrification of CaO-MoO₃-P₂O₅ bio-glasses for clinical applications

¹ Moulay Ismail University Meknes, Faculty of Science and Technology Er-Rachidia, Laboratoire Ingénierie des Matériaux pour Environnement & Ressources Naturelles (IMERN), B.P. 509, Boutalamine, 52000, Morocco ;
² Moulay Ismail University Meknes, National School of Arts and Crafts, Laboratory of Engineering Sciences and Professions, Meknes, Morocco ;
³ Moulay Ismail University Meknes, Faculty of Science and Technology Er-Rachidia, Chemistry-Physics, Electrochemistry, and Environment Team, Faculty of Science and Technology, B.P. 509, Boutalamine, 52000 - Er-Rachidia, Morocco ;
⁴ Cadi Ayyad University, UCA, Laboratory of Materials Physiochemistry and Environment (LPCME), Faculty of Sciences Semlalia, Morocco.

^* Corresponding author: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Bio-glasses with the composition yCaO-(1-y)[xMoO₃-(1-x)P2O₅] (0 ≤ y ≤ 30; x = 50, 67 mol%) were produced. These materials are used in surgery for applications such as bone replacement in orthopaedics, and dental filling. After insertion, they become covered with a layer of carbonated hydroxyapatite, promoting chemical bonds with bone cells that ensure strong adhesion. An in-depth study of their biological and mechanical properties is planned for medical applications. Our study aims to examine in detail the chemical durability and devitrification process of yCaO-(1-y)[0.5MoO₃-0.5P₂O₅] oxide glasses, while establishing a correlation between their structure and properties. This study analyses the evolution of the dissolution rate D_R as a function of CaO content at variable pH and constant temperature, revealing that the dissolution rate does not vary proportionally with the CaO content. It decreases until it reaches a minimum at 10 mol% CaO, after which any further addition causes an increase in DR. We studied chemical compositions with constant P/Mo ratios and presented the results of X-ray diffraction analyses of the associated glasses. The diffractograms of the crystalline glass for the composition (x = 67; y = 30 mol%) show the formation of crystalline phases: CaMoO₄ (JCPDF.08-0144), CaP₄O₁₁ (JCPDF.70-2085), MoP₂O₁₁ (JCPDF.82-1965) and Mo(PO₃)₃ (JCPDF.09-0106).