Gas Phase Carbon Dioxide as an Optimum Substrate for Isocitrate Dehydrogenase Reaction

¹ Department of Bioproducts and Biosystems Engineering, University of Minnesota, Saint Paul, MN 55108, USA
² Department of Petroleum Engineering, University of Houston, Houston, TX 77023, USA

Abstract

As biocatalytic carbon capture has attracted wide attraction due to its high energy efficiency, the preference of carbon species of the reaction is concerned. The self-evolution between carbon species makes the determination of preference a changeling issue. In this study, by comparing the isocitrate dehydrogenase reaction rate profiles with pre-equilibrated and un-equilibrated HCO3--CO2 solutions, gas phase carbon dioxide was believed as the optimum substrate, as it can provide higher reaction rate. During the carbon capture process, the partial pressure of the carbon dioxide affected both the reaction equilibrium and kinetics, while the interfacial area can only determine the reaction rate.