Bridging Nature and Nanotechnology: A Review on the Potential of Herbal Nanoparticles in Medicine

¹ Assistant Professor, Department of Pharmaceutics, School of Pharmacy, RK University -Rajkot- 360002, Gujarat, India, M: +91 9687532287, anjali.patadiya@rku.ac.in
² Professor, Department of Pharmaceutics, School of Pharmacy, RK University - Rajkot- 360002, Gujarat, India
³ Professor, Vardhaman College of Engineering, Hyderabad, India

^* Corresponding author: sonianjali0211@gmail.com

Abstract

Traditional herbal medicine has been an integral part of healthcare systems for centuries, offering numerous healing benefits. However, challenges related to the bioavailability, stability, and precise delivery of herbal treatments have limited their effectiveness. The emergence of nanotechnology offers a promising solution to overcome these constraints by augmenting the accessibility, durability, and targeted delivery of natural herbal components.

This integration of herbal medicine with nanotechnology has led to the development of diverse nanocarrier systems such as nanoparticles, nano capsules, nano emulsions, and nanogels. These innovations notably enhance the solubility and absorption of bioactive compounds present in herbs. Moreover, surface modifications of nanoparticles enable targeted delivery, ensuring specific accumulation at the intended site of action while minimizing off-target effects. Furthermore, nanotechnology allows for controlled release of herbal compounds, resulting in sustained therapeutic effects and reduced dosing frequency, thereby decreasing potential adverse effects associated with high doses.

The application of nanotechnology in herbal medicine has expanded therapeutic possibilities, including treatments for cancer, inflammatory disorders, microbial infections, neurodegenerative diseases, among others. Nano formulations demonstrate promise in amplifying the antioxidant, anti- inflammatory, antimicrobial, & anticancer properties of herbal extracts.

Despite these advancements, challenges such as scalability, regulatory considerations, and long-term safety profiles need attention for widespread clinical adoption. Future research should emphasize standardized manufacturing processes, comprehensive safety assessments, and rigorous clinical trials to evaluate the efficacy and safety of nanotechnology-based natural formulations.

In conclusion, the amalgamation of herbal medicine with nanotechnology offers a transformative approach to overcome inherent limitations and maximize the therapeutic potential of herbal remedies. Continuous interdisciplinary research and development in this field hold the promise of delivering safer, more effective, & precisely targeted herbal-based therapeutics for various health conditions.