| Issue |
E3S Web Conf.
Volume 31, 2018
The 2nd International Conference on Energy, Environmental and Information System (ICENIS 2017)
|
|
|---|---|---|
| Article Number | 06001 | |
| Number of page(s) | 8 | |
| Section | 06. Environmental Health, Toxicology and Epidemiology | |
| DOI | https://doi.org/10.1051/e3sconf/20183106001 | |
| Published online | 21 February 2018 | |
The Effectivity of Green Coconut Water To Reduce Mercury Level In The Blood And To Improve Blood Profiles And Liver Cells Appearance (Study In Sprague Dawley Rats)
1
Doctoral Program of Medical Sciences Diponegoro University, Semarang, Indonesia
2
Faculty of Medicine, Diponegoro University, Semarang, Indonesia
3
Faculty of Public Health, Diponegoro University, Semarang, Indonesia
* Corresponding author: libya6566@yahoo.com
When people are exposed to mercury chloride, it can produce a variety of health effects in the blood and liver. Coconut water contains Zn, Fe, Vit. C, Vit B11, Vit. B6, and Se to reduce mercury chloride level in the blood and improve blood profile and liver cells. Aim of this study was to analysis the effect of green coconut water supplementation in overcoming the toxic effect of Hg chlorid in the blood and liver of Sprague dawley rats exposed to Hg chloride. Samples were randomly about 36 animals rats exposed to HgCl2 through forced feeding by 20 mg/kgBW sondage per day for 14 days, which divided into control group, and intervention groups were given fresh green coconut water in each by 6, 8, and 10 mL/kgBW for intervention 7 and 17 days. The result of this study showed that there is a significant effect and the decrease in mercury levels in the blood. There is no significant affect on the hemoglobin level, hematocrit level and platelet count with the treatment of green coconut water in the mice with exposure Hg. There is no significant effect between treatments using green coconut water with SGPT levels; there is a decrease in SGPT levels at the increasing number of doses of green coconut water and the length of treatment.
© The Authors, published by EDP Sciences, 2018
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (http://creativecommons.org/licenses/by/4.0/).
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