E3S Web Conf.
Volume 34, 2018International Conference on Civil & Environmental Engineering (CENVIRON 2017)
|Number of page(s)||9|
|Published online||19 March 2018|
Endosulfan Toxicity to Anabas testudineus and Histopathological Changes on Vital Organs
School of Environmental Engineering, Kompleks Pusat Pengajian Jejawi 3, Universiti Malaysia Perlis, 02600 Arau, Perlis, Malaysia.
2 Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, UPM 43400 Serdang, Selangor, Malaysia.
* Corresponding author: email@example.com
The toxicity of endosulfan, an organochlorine type insecticide to a commonly consumed freshwater fish species, A. testudineus (40.68±9.03 g; 13.49±0.99 cm), was investigated under static conditions. The nominal endosulfan concentrations ranging from 10 to 80 μg/L subjected to the fish population results in 96-hour median lethal concentration, LC50, of 35.2±3.99 μg/L. The toxicity is a function of both endosulfan concentration and exposure time (p>0.05). Histopathological analysis on vital organs exposed to sublethal concentrations indicates that structural changes started at sublethal dose and the effects aggravated with increasing endosulfan concentration. Gill was found to experience aneurism, hyperplasia in lamellar and autolysis of mast cell. Pyknotic nuclei and necrosis were observed in liver cell, while the lumen of renal tubule was found to narrow and haemorrhage was observed in cytoplasm cell. High LC50 compared to other fishes indicates that A. testudineus has high tolerant to endosulfan, however, endosulfan slowly alters the fish biochemistry and is potentially transferable to human
© The Authors, published by EDP Sciences, 2018
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (http://creativecommons.org/licenses/by/4.0/).
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