E3S Web Conf.
Volume 145, 20202019 International Academic Exchange Conference on Science and Technology Innovation (IAECST 2019)
|Number of page(s)||8|
|Section||International Conference on Biotechnology and Food Science|
|Published online||06 February 2020|
Advances in the mechanisms of Hibiscus sabdariffa L. on hypertension
1 Guangzhou College of Technology and Business, Guangzhou, Guangdong, 510850, China
2 School of Food Sciences and Engineering, South China University of Technology, Guangzhou, Guangdong, 510460, China
a Corresponding author’s e-mail: email@example.com
As a traditional edible beverage and medicinal application for high-pressure blood treatment with no side effects, Hibiscus sabdariffa L. (HS) has high prospect to be nutraceuticals as diet additive for anti-hypertension. The anti-hypertension effect of HS has also been scientific validated recently especially in diabetic patient and post-partum mothers. In this paper, we reviewed up-to-date mechanisms found for the anti-hypertensive effect of HS extracts. Those included the inhibition of angiotensin-converting enzymes (ACE) activity, diuretic effect, endothelium-derived nitric oxide-cGMP-relaxant pathway and inhibition of calcium (Ca2+)-influx into vascular smooth muscle cells, cholinergic and/or histaminergic mechanisms, reduction in the diffusion distance between capillaries and myocytes as well as new vessel formation. Phenolic acids, anthocyanins (e.g. cyanidin-3-sambubioside and delphinidin-3-sambubioside) and anthocyanin metabolites probably contribute mostly to the hypotensive activity.
© The Authors, published by EDP Sciences 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.