E3S Web Conf.
Volume 164, 2020Topical Problems of Green Architecture, Civil and Environmental Engineering 2019 (TPACEE 2019)
|Number of page(s)||8|
|Section||Agriculture and Biotechnologies|
|Published online||05 May 2020|
Comparative biological and antiquorum activity of extracts of lamiaceae plants, grown in the Russian Federation
Federal Research Center of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, Yanvarya St., 29, 9, Orenburg, 460000, Russia
* Corresponding author: email@example.com
The purpose of this study was to assess the biological activity and antiquorum activity of extracts of Lamiaceae plants. Material and methods. Extracts of 4 medicinal plants of the Lamiáceae were used as test substances. Bioluminescent analysis were used on the model Escherichia coli MG1655 and antiquorum activity of medicinal plant extracts - on the model Chromobacterium violaceum ATCC 31532. Result. An analysis of the bioluminescent testing of Mentha piperita leaf aqueous extract showed no toxic effect throughout the entire record period over the entire concentration range. Low concentrations of analyte (0.625 mg/ml - 0.0097 mg/ml) cause a slight induction of lux-operon. Sālvia officinālis extract showed a slight antibacterial effect on the tested strain (EC50 = 10 mg/ml). The effect is achieved after 50-60 minutes of contact of microbial cells with components of Sālvia officinālis extract and persists until the end of the analyzed period of time (180 minutes). Extract of Oríganum vulgáre showed a decrease in the level of luminescence by 30% when the analyte was exposed to a concentration of 10 mg/ml. The extract of Thýmus serpýllum showed a pronounced antibacterial effect on the test organism, with a maximum concentration of 10 mg/ml, a 50% inhibition of luminescence is observed. All the tested compounds in subinhibitory concentrations suppressed the quorum-dependent biosynthesis of violacein.
© The Authors, published by EDP Sciences 2020
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