E3S Web Conf.
Volume 175, 2020XIII International Scientific and Practical Conference “State and Prospects for the Development of Agribusiness – INTERAGROMASH 2020”
|Number of page(s)||6|
|Section||Livestock and Veterinary|
|Published online||29 June 2020|
Approaches to probiotics properties testing using Caco-2 cells
Southern Federal University, 194/1, Stachki Prospect, 344090, Rostov-on-Don, Russian
2 Agricultural Research Center «Donskoy», 3, Nauchny gorodok str., Zernograd, Rostov region, Russia
3 Don State Technical University, 1, Gagarin sq., 344003, Rostov on Don, Russia
4 Non profit JSC “Zhangir Khan West Kazakhstan Agrarian Technical University”, 51, Zhangir khan street, 090009, Uralsk, Kazakhstan
* Corresponding author: firstname.lastname@example.org
Adequate biological models are a prerequisite to screening and development of probiotic drugs. In the present study, Caco-2 cell line is reviewed as a model for analyzing properties of probiotics. This cell culture possesses all the characteristics necessary for evaluating the effects of probiotic drugs on a wide range of both intracellular processes and intercellular interactions. Informativeness of Caco-2 cells is in the focus of the present review.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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