E3S Web Conf.
Volume 185, 20202020 International Conference on Energy, Environment and Bioengineering (ICEEB 2020)
|Number of page(s)||10|
|Section||Medical Biology and Medical Signal Processing|
|Published online||01 September 2020|
Regulation of Caenorhabditis Elegans model in Alzheimer’s Disease
Yew Chung International School – Secondary School, Hong Kong, 999077, China
* Corresponding author: firstname.lastname@example.org
Alzheimer’s disease (AD) is affecting numerous families and individuals around the world nowadays, as the exact reason is still undetermined. At this stage, developmental treatment displays a particularly significant role in relieving symptoms for the patients. Currently, the two most well-known factors that have impacts on the diagnosis of AD are the plaques and tangles formed from amyloid-beta and tau protein. Modelling for Alzheimer’s disease is essential in understanding targeted aspects of the disease, while Caenorhabditis elegans (C.elegans) was chosen as a pivotal model. C.elegans presents dramatic priorities using orthologs for the study of AD, especially in examining the formation of the deposits and the regulations of specific gene expressions that result in this abnormality. This review discusses the properties, which C.elegans shows on the study of AD, and the achievements that have been approached using this model, as well as what other models are being tested by scientists. Properties of other models, which can overwhelm C.elegans, as well as the expectations for future modelling systems on AD are examined as well.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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