E3S Web Conf.
Volume 213, 20202nd International Conference on Applied Chemistry and Industrial Catalysis (ACIC 2020)
|Number of page(s)||3|
|Section||Industrial Catalysis and Chemical Substance R&D and Application|
|Published online||01 December 2020|
Synthesis and antibacterial activity of modified ε-polylysine
College of Chemistry and Materials Engineering, College of Food Science and Technology, Bohai University; Food Safety Key Lab of Liaoning Province; National & Local Joint Engineering Research Center of Storage, Processing and Safety Control Technology for Fresh Agricultural and Aquatic Products; Bohai University, Jinzhou, 121013, China.
* Corresponding author: firstname.lastname@example.org (K. Zhong)
In this paper, Ugi reaction was used to synthesize the modified polylysine (M-ε-PL) in two steps, and OD value was measured by ultraviolet spectrophotometer to determine the inhibitory rate of M-ε-PL in different concentrations of Escherichia coli and Staphylococcus aureus. The results showed that the antibacterial effect was better with the increase of concentration of M-ε-PL. Among them, 20 mg/mL M-εPL had better bacteriostatic effect on E. coli and S. aureus. The antibacterial rate was 70% and 44%.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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