An Observation on Curative Effect of Dahuang-Mudan Decoction among Patients Receiving Postoperative Chemotherapy of Colon Carcinoma

College of traditional Chinese medicine, Hainan Medical College, Haikou， 571100 ， China

Abstract

PURPOSE This thesis focuses on the research of the observation of curative effect of Dahuang-Mudan decoction(DMD) applied among the patients receiving chemotherapy in post operation of colon carcinoma. METHOD The selected cases of research have been 130 postoperative patients of colon carcinoma who had acquired hospitalization in some tertiary-grade A class hospital from June 2018 to December 2019, all of which are devided into two respetive groups by random number-- the Routine Group(RG) and the Contrast Group(CG), each containing 65 cases. Patients in RG get solely chemotherapy for rehabilitation, while the use of DMD is being added to patients in CG on the basis of standards in RG. After a certain period of treatment, some contrasts would be done in overall efficacy rate, the first anal exsufflation in post-operation, possibilities of complication and quality evaluation on life. RESULT After related treatment of DMD, patients in CG perform remarkably better in aspects of overall efficacy, the first anal exsufflation in post-operation, possibilities of complication occurence and quality evaluation on life than those in RG. CONCLUSION The use of DMD for postoperative patients of colon carcinoma who are receiving chemical treatment produces remarkable curative effect and vast value of clinical application, thus further promotion and practice could be positively adopted.

Colon carcinoma is clinically a malignant tumor frequently affecting in digestive system, occurring at the connection of sigmoid colon and rectum. With the continueous change of people’s diet constructure and tempo of life, the morbidity toll of colon carcinoma has seen a tendency of increase year by year. The age section of most of patients mainly lays between 35 to 55 years old in clinical, while male patients have suffered a higher morbidity than female ones, and the gender ratio could be a near 2:1[1]. The aetiological agent of colon carsinoma could be tightly connected to a diet that is high in fat and low in dietry fiber. A preference for high-fat food with low dietry fiber may incur chronic colonitis and intestinal polyps, which may further deteriorate into colon carcinoma. For clinical front line, the main method for the treatment of colon carcinoma is related operation at its core, along with a variety of postoperative adjuvant therapies. Western medicine tends to adopt chemotherapy, but the clinical effect could be less ideal for the patients while a number of side-effects may also emerge easily. The chinese traditional medicine tends to apply a dialectic therapy at core for the treatment, and the combination therapy including dialectic therapy and chemotherapy has gradually become a mainstream method for the treatment of colon carcinoma due to facual effectiveness of ameliorating curative-effects and reducing side-effects[2]. This research focuses on an analysis of the actual clinical curative-effects of DMD applied on patients who are receiving postoperative chemotherapy of colon carcinoma.