| Issue |
E3S Web Conf.
Volume 245, 2021
2021 5th International Conference on Advances in Energy, Environment and Chemical Science (AEECS 2021)
|
|
|---|---|---|
| Article Number | 03089 | |
| Number of page(s) | 5 | |
| Section | Chemical Performance Research and Chemical Industry Technology Research and Development | |
| DOI | https://doi.org/10.1051/e3sconf/202124503089 | |
| Published online | 24 March 2021 | |
Research on the synthesis of chitosan@MIL-100(Fe)
College of Pharmacy, Anhui Xinhua University, Anhui, Hefei, 230088
* Correspondence should be addressed to SONG Zurong; songzurong@axhu.edu.cn
Objective: Studying new carrier materials to solve the problems of bioavailability and side effects of drugs in the body and choose the suitable carrier to coat the drug. This carrier not only improves the release and absorption of drug molecules in the body, but also significantly improves the bioavailability and reduces the toxic side effects of high concentrated drugs. Therefore, this paper focuses on the research of the synthesis of a new carrier material.
Methods:Using ferric nitrate as iron source, first add ferric nitrate, 1,3,5-benzene tricarbonic acid, chitosan solution and deionized water pro rata, then synthesize the product using mechanical stirring, and purify and dry the product.
Results:The maximum yield of chitosan is obtained when the concentration of chitosan is 1% using mechanical stirring method, and the yield is 0.6330 g.
Conclusion:The results show that the thinner the concentration of chitosan solution is, the better synthesizes the chitosan@MIL-100(Fe) and the higher the yield is. And it reaches the best result when the concentration is 1%.
© The Authors, published by EDP Sciences, 2021
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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