| Issue |
E3S Web Conf.
Volume 261, 2021
2021 7th International Conference on Energy Materials and Environment Engineering (ICEMEE 2021)
|
|
|---|---|---|
| Article Number | 02028 | |
| Number of page(s) | 4 | |
| Section | Energy Chemistry Performance and Material Structure Analysis | |
| DOI | https://doi.org/10.1051/e3sconf/202126102028 | |
| Published online | 21 May 2021 | |
Effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor)
1
College of Life Sciences, China JiLiang University, Hangzhou, Zhejiang, 310007, China
2
Technology center of Hangzhou Customs District P. R. China, Hangzhou, Zhejiang, 310018, China
XiaSha Higher Education Zone, Mailing address: #258 XueYuan Street Hangzhou, 310018, Zhejiang Province, People’s Republic of China.
* E-mail: gejian16888@163.com
The study was conducted to evaluate the effect of water temperatures and intraperitoneal administration of microcystins (MCs) on the pharmacokinetics characteristics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) by RP-HPLC method. The results showed that EGCG was absorbed and eliminated more faster at 20ºC than at 10ºC. Then the detected results also showed that EGCG was significantly absorbed fast in MCs-treated group than in control group. However, EGCG elimination became very lowly in MCs-treated group. Therefore, the pharmacokinetic characteristics of EGCG were significantly affected by water temperature and MCs toxin.
© The Authors, published by EDP Sciences, 2021
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.