E3S Web Conf.
Volume 290, 20212021 3rd International Conference on Geoscience and Environmental Chemistry (ICGEC 2021)
|Number of page(s)||4|
|Section||Environmental Chemistry and Chemical Technology Application|
|Published online||14 July 2021|
Chiral phosphoric acid and its applications of asymmetric catalytic hydrogenation
School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, 300072, China
* Corresponding author’s e-mail: SUNZX@tju.edu.cn
As an excellent representative of organic small molecular catalysts, chiral phosphoric acid played an important role in asymmetric catalytic hydrogenation. According to the skeleton of chiral phosphoric acid, the development and applications of chiral phosphoric acid were summarized. The applications of chiral phosphoric acid in asymmetric catalytic hydrogenation were introduced according to three kinds of hydrogen source systems used in chiral phosphoric acid catalytic reaction. It was found that chiral phosphoric acid has high activity and excellent selectivity. Chiral products with excellent yields and enantioselectivities were obtained in most reactions.
© The Authors, published by EDP Sciences, 2021
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