Issue |
E3S Web Conf.
Volume 335, 2022
The 2nd International Conference on Environmentally Sustainable Animal Industry (The 2nd ICESAI 2021)
|
|
---|---|---|
Article Number | 00006 | |
Number of page(s) | 5 | |
DOI | https://doi.org/10.1051/e3sconf/202233500006 | |
Published online | 14 January 2022 |
A bivalent vaccine of Eimeria media and Eimeria intestinalis yields protective immunity against coccidiosis during rabbit production
1 Department of Animal Sciences, Universitas Sebelas Maret, Surakarta 57126, Indonesia
2 Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia
* Corresponding author: pennyhumaidahhamid@staff.uns.ac.id
Coccidiosis is the costliest disease in the rabbit industry. The kits do not obtain maternal immunity against the diseases and therefore suckling to weaning period being the riskiest time of infection. To date, control of coccidiosis is relied on the use of chemical coccidiostat as a drug or as the substance in feed. Whilst, continuous exposure to antibiotics develops resistance and contamination in the carcass. There is no commercially provided vaccine to prevent rabbit coccidiosis cases. In this report, we processed precocious lines from the strain of Yogyakarta origin by using selection pressure to attenuate Eimeria spp. The vaccine candidate composed of 50% of each Eimeria media and Eimeria intestinalis were given orally to initiate protective immunity against rabbit coccidiosis. The vaccinated groups with 5 x 102 oocyst dosage exhibited 95% less total oocyst excretion compared to the non-vaccinated group. Our experiment showed no mortality and without any significantly detrimental response of vaccinated rabbits during the observation time (P<0.0001). Since the oocysts in the vaccinated rabbits are excreted in dropped faecal samples, it provides recirculation and provokes a group immunity within the flock. A vaccine candidate is a promising tool as a more environmentally friendly strategy for sustainable rabbit production.
© The Authors, published by EDP Sciences, 2022
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.