Utilization of Green Tea Extract on Anti-aging Cream with Butylated Hydroxytoluene (BHT) and Tertiary Butylhydroquinone (TBHQ): Physical Stability Aspect

¹ Department of Pharmaceutics, Faculty of Pharmacy, University of Surabaya, Jl Tenggilis Mejoyo, Kali Rungkut, Surabaya 60293, East Java, Indonesia
² Department of Pharmaceutics and Formula Development, Faculty of Pharmacy, University of Indonesia, Cluster of Health Sciences Building, Depok, West Java 16424, Indonesia
³ Faculty of Applied Health Sciences, Department of Medical Laboratory Sciences, The Hashemite University, PO Box 330127, 13133 Zarqa, Jordan
⁴ Molecular Biology and Genetics, The Hashemite University, 13133 Zarqa, Jordan

^* Corresponding author: c_avanti@staff.ubaya.ac.id

Abstract

Green tea (Camellia sinensis (L.) Kuntze) is a potent natural ingredient with flavonoid content that can be used as an antioxidant and anti-aging for skincare products. The formula containing green tea extract is usually formulated as oil in water emulsion or cream. The active components of green tea are catechins which are characterized as less stable against oxidation. Therefore, it is needed to add other antioxidants such as ButylatedHydroxy Toluene (BHT) and Tertiary–Butyl Hydroquinone (TBHQ) to protect the product from degradation. The aim of this study was to obtain a physically stable antiaging cream formula. Each formula was tested for physical stability by measuring several variables including organoleptic, pH, relative density, viscosity, and flow properties, as well as droplet size. Accelerated stability testing is carried out for 3 mo at 40 °C and 75 % relative humidity. The results found that cream with the BHT formula is more stable than the TBHQ formula in terms of the parameters of density and droplet size. While the TBHQ formula only gave better stability in pH, the other variables from both formulas remain stable in 3 mo. It can be concluded that the green tea extract cream with BHT antioxidant is more stable than the TBHQ.