| Issue |
E3S Web Conf.
Volume 460, 2023
International Scientific Conference on Biotechnology and Food Technology (BFT-2023)
|
|
|---|---|---|
| Article Number | 11014 | |
| Number of page(s) | 11 | |
| Section | Functional Foods, Food and Health | |
| DOI | https://doi.org/10.1051/e3sconf/202346011014 | |
| Published online | 11 December 2023 | |
Genetic study of the metabolic syndrome in the Moroccan population: A scoping review
1 Cellular Biology and Molecular Genetics Laboratory, Sciences Faculty, Ibn Zohr University, Agadir, Morocco, Postcode 80000.
2 Virology Unit, Viral Hepatitis Laboratory, Pasteur institute, Casablanca, Morocco, Postcode 20360
3 Sciences of Health and Environment Laboratory; Team of Biotechnology, Environment and Health; Higher Institute of Nursing Professions and Health Techniques, (ISPITS) Agadir, Morocco, 6
* Corresponding author: najehhami@yahoo.fr
Complications of metabolic syndrome include cardiovascular disease and type 2 diabetes mellitus for different ethnic populations, which represent a growing public health burden. The identification of genetic factors contributing to the metabolic syndrome is of great interest for the prevention and treatment of cardiovascular diseases in Morocco. This scoping review summarizes the available data on genetic variants associated with metabolic syndrome in the Moroccan population. Electronic searches of PubMed and EMBASE databases were conducted to identify all studies published from January 2000 to 2022, on genetic susceptibility to metabolic syndrome in the Moroccan population. The studies included in this review met the pre-specified inclusion criteria. Studies included in this review matched the requirements for inclusion. Five research targeted genetic variations as their main subject. Data were narratively summarized since the studies were high degree of heterogeneity. There was a total of thirteen polymorphisms in the eight metabolic syndrome susceptibility genes that had different effects and were linked to characteristics in the Moroccan population. There is a clear need to improve our understanding of the genetic causes of the metabolic syndrome. This is the first review to comprehensively and rigorously summarizes the available data on the genetic determinants of the metabolic syndrome, a major contributor to the cardiovascular diseases burden of the Moroccan population.
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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