| Issue |
E3S Web Conf.
Volume 491, 2024
International Conference on Environmental Development Using Computer Science (ICECS’24)
|
|
|---|---|---|
| Article Number | 03007 | |
| Number of page(s) | 6 | |
| Section | Health Development | |
| DOI | https://doi.org/10.1051/e3sconf/202449103007 | |
| Published online | 21 February 2024 | |
A Investigation of Kidney Function in the Hypo-Thyroidism Individuals at the Tertiary Healthcare Centre
1 Associate Professor Dept. of General Medicine Dr. Rajendra Gode Medical College, Amravati
2 Professor Dept. of Biochemistry Dr. Rajendra Gode Medical College, Amravati.
3 Tutor Dept. of Biochemistry Dr. Rajendra Gode Medical College, Amravati
4 Lecturer Dept. of Pharmacology Dr. Rajendra Gode Institute of Pharmacy, Amravati
5 Assistant Professor Dept. of Mechanical Dr. Rajendra Gode Institute of Technology and Research, Amravati
6 Professor Dept. of Preventive and Social Medicine Dr. Rajendra Gode Ayurvedic College and Hiospital, Amravati
1 Corresponding author: namitavarghese@outlook.com
The most prevalent endocrine illnesses worldwide are thyroid disorders. India is also no different. There are thought to be 42 million thyroid ailment sufferers in India, based on projections from numerous research on the condition. to investigate Kidney function in hypo-thyroid individuals at a tertiary medical facility. This cross-sectional investigation was conducted over a one-year period in 100 hypo-thyroid individuals at a Medical College and Hospital in Central India after receiving approval from the institutional ethical committee. The investigation includes similar euthyroid participants in addition to the diagnosed hypo-thyroidism individuals who provided consent. Both groups underwent the kidney function test, which included indicators such as creatinine clearance, creatinine urea, and uric acid, among others. Unpaired t-test statistics were computed using SPSS version 22 software. 49 -16%, 50-59 12%, and >60 10%. Women individuals made up 66% of the total population, with male individuals making up 24%. The Creatinine Clearance was considerably poorer in the hypo-thyroidism individuals compared to controls, measuring 102.08±9.98, 80.74±10.56 (P 0.001), Creatinine -0.82±0.102, 0.726±0.0456 (P 0.001), Urea -28.18±3.18, 21.82±3.01 (P 0.001), and Uric acid - 5.082±0.7614, 3.124±0.158 (P 0.001). According to the results of our investigation, the majority of hypo-thyroid individuals were women and in the age range of 30-39. They also demonstrated significantly abnormal kidney function tests, such as lower creatinine clearance and higher creatinine, urea, and uric acid levels in comparison to euthyroid individuals.
Key words: Hypo-thyroidism / Euthyroid / Kidney function Test / Creatinine Clearance / Creatinine Urea / Uric acid
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.