Electrochemical detection of ofloxacin with MoS₂/RGO composite sensor

Department of Chemistry, Chandigarh University, Punjab

Abstract

This work presents the development and utilization of a MoS₂/RGO nanocomposite sensor for the quantification of ofloxacin. The fabrication of this sensor is based on the combination of graphite oxide and MoS₂ as fundamental components. The special shape ordered atomic arrangement, and flatness of the MoS₂/RGO nanocomposite have made the sensor more sensitive and able to detect smaller amounts of the target substance. Cyclic voltammetry was employed in the sensing investigation, where the relationship between current and potential was explored using a modified glassy carbon electrode. The data explicitly demonstrates that MoS₂/RGO exhibits a substantially higher peak current (22.0–33.9 µA) and considerably lower overpotential (0.27–0.12 V) compared to MoS₂ alone. This translates to a significant enhancement in sensitivity (89.89 A/cm²) and detection limit (18.89 µM) for MoS₂/RGO. These remarkable improvements are attributed to the nanocomposite's facilitated charge transfer, increased specific surface area, and superior conductivity.