| Issue |
E3S Web of Conf.
Volume 553, 2024
2024 International Conference on Ecological Protection and Environmental Chemistry (EPEC 2024)
|
|
|---|---|---|
| Article Number | 04010 | |
| Number of page(s) | 6 | |
| Section | Advanced Technologies and Applications | |
| DOI | https://doi.org/10.1051/e3sconf/202455304010 | |
| Published online | 24 July 2024 | |
Research progress on the application of aspirin and its derivatives in the treatment and rehabilitation of cardiovascular diseases
College Of Pharmacy, Editorial Department, Nanchang Medical College, Xiaolan Economic Development Zone, Nanchang, 330052 Jiangxi, China
* Corresponding author: pents@pentsme.com
This article systematically reviews recent advancements in the use of aspirin for the prevention and treatment of cardiovascular diseases, highlighting its ongoing exploration of new pharmacological activities. Initially, the review details the pharmacological activities and associated drug toxicities of aspirin, followed by an overview of its clinical applications in recent years. Through methods such as literature review and comparative data analysis, this study evaluates the efficacy and safety of three types of aspirin derivatives: nitric oxide aspirin derivatives, hydrogen sulfide-nitric oxide derivatives, and unsaturated fatty acid aspirin derivatives. The review emphasizes their potential in reducing toxic side effects. Additionally, the latest clinical research is examined to elucidate the effects and mechanisms of these drugs in clinical settings. The article concludes by summarizing the current risks associated with aspirin derivatives in cardiovascular disease research and suggests possible future research directions.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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