The impact of the ketogenic diet on Alzheimer’s disease

Department of Biology, University of Washington, WA 98105, United States

^* Corresponding author: minzhi@uw.edu

Abstract

Alzheimer’s disease (AD) is a neurological illness that causes memory loss and mental decline. Many are contemplating a Ketogenic diet (KD) as an Alzheimer’s treatment due to its neuroprotective effects. By modifying brain metabolism, decreasing inflammation, and guarding against neurodegenerative processes, KD halts cognitive decline, enhances cognition, and gives therapeutic advantages. According to prior research, the KD combats inflammatory and apoptotic mediators in Alzheimer’s, protects brain cells, and influences amyloid plaques and tau protein. Animal and human research studies illustrate that the KD and supplements remedy brain inflammation, cognition, and metabolism. The KD works better with other AD treatments like exercise, forming a multi-domain strategy. However, the present research is frequently small and short-term, requiring big, long-term trials for more convincing data. This study suggests that optimizing the KD, evaluating particular fat sources, and constantly monitoring carbohydrate consumption are essential to achieve promising cognitive function and quality of life improvements. However, large-scale, long-term research and diet optimization is needed to fully understand the diet’s effect and potential to improve Alzheimer’s patients’ lives.