Issue |
E3S Web of Conf.
Volume 553, 2024
2024 International Conference on Ecological Protection and Environmental Chemistry (EPEC 2024)
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Article Number | 05031 | |
Number of page(s) | 5 | |
Section | Medical Treatments and Therapies | |
DOI | https://doi.org/10.1051/e3sconf/202455305031 | |
Published online | 24 July 2024 |
Immunotherapy in Breast Cancer: Situation and Challenge
Medical school, Dalian University, Dalian, 116622, China
* Corresponding author: asolis81621@student.napavalley.edu
Breast cancer (BC) is a huge worldwide health concern that necessitates novel therapeutic approaches. Immunotherapy has emerged as a promising avenue, leveraging the immune system’s intrinsic capabilities to combat malignancies. This review examines the mechanisms, recent advances and future prospects of BC immunotherapy using monoclonal antibodies (MABs), immune checkpoint inhibitors (ICIs), cytokines, vaccines and CAR T-cells. The objective of this paper is to offer a comprehensive understanding of the complexities of immunotherapeutic methods, their mechanisms of action, and their potential influence on the treatment of BC. Studies have found that MABs provide targeting precision, ICIs disrupt immune evasion, cytokine therapies modulate immune responses, vaccines stimulate anti-tumor immunity, and CAR T cells provide personalized immune modulation. Clinical trials have showcased encouraging outcomes, particularly in aggressive and metastatic cases. However, Immunotherapy in BC treatment faces limitations such as varying responses among patients and the development of resistance mechanisms by cancer cells. Further research is needed to address these challenges and enhance the effectiveness of this approach.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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