Issue |
E3S Web Conf.
Volume 564, 2024
International Conference on Power Generation and Renewable Energy Sources (ICPGRES-2024)
|
|
---|---|---|
Article Number | 07003 | |
Number of page(s) | 6 | |
Section | Signal Processing | |
DOI | https://doi.org/10.1051/e3sconf/202456407003 | |
Published online | 06 September 2024 |
Creation and Assessment of Herbal Gel with Guava Leaf Extract
1 Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Dundigal, Hyderabad
2 Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Dundigal, Hyderabad
3 Department of Analysis, Marri Laxman Reddy Institute of Pharmacy, Dundigal, Hyderabad
* Corresponding author: kdeepika1184@gmail.com
Mouth ulcers, a common oral mucosal disorder, can cause discomfort and interfere with daily activities. Natural remedies like guava leaves extract have shown promising potential in managing such conditions due to their anti-inflammatory and antimicrobial properties. This study aimed to formulate and evaluate an aqueous gel of guava leaves extract for the treatment of mouth ulcers. The guava leaves extract was prepared using a maceration method and incorporated into a gelbase consisting of Carbopol 934P. Various formulations were prepared with different concentrations of guava leaves extract to optimize the formulation for maximum efficacy. The formulated gels were evaluated for their physicochemical properties, including pH, viscosity, spreadability, and drug content. The results indicated that the formulated aqueous gel exhibited desirable physicochemical properties, with optimal viscosity and spreadability for application on oral mucosa. The release studies demonstrated sustained release of active constituents from the gel matrix, ensuring prolonged therapeutic effect. Moreover, the optimized gel formulation showed significant antimicrobial activity against oral pathogens, suggesting its potential for managingmouth ulcers. In conclusion, the formulated aqueous gel of guava leaves extract holds promise as aneffective and natural treatment option for mouth ulcers.
Key words: Mouth ulcers / guava leaves extract / aqueous gel / formulation / evaluation / antimicrobial activity / wound healing
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.