Issue |
E3S Web Conf.
Volume 632, 2025
The 5th Edition of Oriental Days for the Environment “Green Lab. Solution for Sustainable Development” (JOE5)
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Article Number | 01007 | |
Number of page(s) | 5 | |
Section | Natural Resources, Earth & Environmental Studies | |
DOI | https://doi.org/10.1051/e3sconf/202563201007 | |
Published online | 03 June 2025 |
Evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from Pancratium foetidum Pom. (Moroccan Endemic Amaryllidaceae)
1 Natural Resources and Environment Laboratory, Biology Chemistry Geology Department, Polydisciplinary Faculty of Taza, Sidi Mohamed Ben Abdellah University, Fez 30050, Morocco.
2 Laboratory of Applied Chemistry and Environment –ECOMP, Faculty of Sciences, Mohamed 1st University, Bd Mohamed VI, BP: 717, Oujda 60000, Morocco
3 Higher Institute of Nurses Professions and Health Techniques of Agadir, Annex of Guelmim – Morocco.
4 Higher Institute of Nursing Professions and Health Techniques (ISPITSO), Oujda, Morocco.
5 Environment and Health Team, Polydisciplinary Faculty of Safi, Cadi Ayyad University, Safi, Morocco.
6 Laboratory of bioresources, biotechnology and health, faculty of sciences, mohammed first university, 60000 oujda maroc
7 Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Ajman University, PO Box: 346 Ajman, UAE.
8 Department of Biology, Mohammed v University, Faculty of Science, Rabat, Morocco
9 Laboratory of Applied Chemistry and Environment (LCAE), Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco
* Corresponding author: y.elouadi@ump.ac.ma
Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant family. It has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. The antispasmodic activity was investigated in vitro using rabbit intestine, and the antioxidant activity was evaluated by DPPH assay. The results indicated that lycorine has an irreversible relaxant property on the isolated rabbit jejunum. Whereas, it did not show a significant antioxidant activity toward the DPPH free radical in comparison with ascorbic acid.
© The Authors, published by EDP Sciences, 2025
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