| Issue |
E3S Web Conf.
Volume 681, 2025
4th Energy Security & Chemical Engineering Congress (ESChE 2025)
|
|
|---|---|---|
| Article Number | 02002 | |
| Number of page(s) | 6 | |
| Section | Biomass, Agrowaste Valorization and Bio-Based Products | |
| DOI | https://doi.org/10.1051/e3sconf/202568102002 | |
| Published online | 22 December 2025 | |
Synthesis of α-Glycerol Mono Caprylate from Protected Glycerol
1 Department of Chemistry, Faculty of Science and Engineering, University of Nusa Cendana, Kupang, Indonesia
2 Mechanical Engineering Department, Faculty of Science and Engineering, University of Nusa Cendana, Kupang, Indonesia
3 Chemical Engineering Department, Faculty of Chemical & Natural Resources Engineering, Universiti Malaysia Pahang, Pahang, Malaysia
4 Department of Pharmacy, Health Polytechnic of Kupang, Kupang, Indonesia
* Corresponding author: febri_nitbani@staf.undana.ac.id
The synthesis of α-glycerol mono caprylate from protected glycerol has been carried out through a two-step reaction process. The transesterification reaction of methyl caprylate and protected glycerol (ratio 1:4) in the presence of 5% K2CO3 (w/w of the total reactant) as a catalyst and solvent-free produced a 1,2-acetonide-3-caprylil glycerol as a yellow viscous liquid with 61.8 % yield. The deprotection reaction of 1,2-acetonide-3-caprylil glycerol using Amberlyst-15 in ethanol for 20 hours at room temperature yielded crude α-glycerol monocaprilate. Purification of α-glycerol mono caprylate using hydro alcohol and n-hexane to produce a white solid with a yield and purity of 63.4% and 100%, respectively.
Key words: protected glycerol / monoglyceride / methyl caprylate / monocaprylin
© The Authors, published by EDP Sciences, 2025
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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