| Issue |
E3S Web Conf.
Volume 271, 2021
2021 2nd International Academic Conference on Energy Conservation, Environmental Protection and Energy Science (ICEPE 2021)
|
|
|---|---|---|
| Article Number | 04037 | |
| Number of page(s) | 9 | |
| Section | Environmental Materials and Solid Waste Recycling Technology | |
| DOI | https://doi.org/10.1051/e3sconf/202127104037 | |
| Published online | 15 June 2021 | |
Review the Regulation of Plasma Membrane Calcium Channel in Cancer and Patch Clamp Technique
1 School of Biological Science, University of Edinburgh, Edinburgh city, EH91PH, The United Kingdom ;
2 Lakehead University, Thunder Bay, Ontario, P7B5E1, Canada ;
*a Corresponding author: s1918283@ed.ac.uk
b qfang1@lakeheadu.ca
† These authors contributed equally.
As one of the most versatile and universal second messengers, calcium plays an essential role in cell life. Here we briefly reviewed the research progress of how different calcium channels are located at the cell plasma membrane, including voltage-gated calcium channels (VGCCs), receptor-operated channels (ROC), and store-operated channels (ROC). These channels can regulate different cancer progression. Afterward, the patch clamp technique's development and operating principle, an important quantitative method used for ion channel investigation, are introduced in this paper.
© The Authors, published by EDP Sciences, 2021
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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