E3S Web Conf.
Volume 161, 2020International Conference on Efficient Production and Processing (ICEPP-2020)
|Number of page(s)||6|
|Published online||15 April 2020|
Man-made load of industrial environment and its impact on human microbiota
1 Doctor of Science (Biology), Chair of Fundamental Medicine and Biology, Professor Institute of medicine and experimental biology, director, Pskov state university, Russia
2 Doctor of Science (Biology), Chair of Zoology and Animals Ecology, Professor. Pskov state university, acting rector, Russia
3 Doctor of Science, (Engineering), professor, Higher school of biotechnology and food technologies of Peter the Great polytechnic university in Saint Petersburg, Russia
4 Cand.Sc. (Engineering), associate professor, Higher school of biotechnology and food technologies of Peter the Great polytechnic university in Saint Petersburg, Russia
5 Cand.Sc. (Chemistry), Chair of chemistry, associate professor, Pskov state university, Russia
* Corresponding author: Makarovayulia169@mail.ru
People are exposed to a significant amount of man-made hazards upon contact with technological systems, and foundry engineering industrial sites belong undoubtedly to such systems. Foundry shops are characterized by high noise and temperature thresholds that affect the human body. Unsatisfactory condition of the air is considered to be an acute problem in foundry engineering. In this connection, the state of air and its composition change, which can certainly affect health of workers, and the latter may be seen in the respiratory, cardiovascular, nervous systems, and digestive organs functional changes. However, up to date, the effect of health hazards of foundry engineering on the microbiocenosis of human intestine remains poorly studied. The paper apprizes the microbiota of human large intestine being exposed to integrated effects of foundry engineering factors. A structural change of the intestinal coenotype accompanied by a change of absolute dominants and opportunistic microorganisms appearance is established. Intestinal microbiocenosis disorder is accompanied by a high detectability of parasitic protozoa Blastocystis spp. in the sampling material. The obtained blastocyst isolates have pathogenic properties of varying degree of manifestation, which indicates their unequal etiological significance in the development of the pathological process. The isolated strains of protozoa have a high anti-interferon activity characterizing their persistent properties. This characteristic brings along the displacement of normal symbionts by blastocysts and colonization of the intestinal mucous membranes with these protozoa.
© The Authors, published by EDP Sciences, 2020
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