E3S Web Conf.
Volume 176, 2020International Scientific and Practical Conference “From Inertia to Develop: Research and Innovation Support to Agriculture” (IDSISA 2020)
|Number of page(s)||6|
|Section||Resource-Saving Technologies, Technical Means and the Digital Platform of the Agro-Industrial Complex|
|Published online||22 June 2020|
Scientific justification of the formula composition of biotechnological form of BAA with directed functional properties
1 Ural State University of Economics, 620144 Ekaterinburg, Russian Federation
2 Kemerovo State Medical University, 650029 Kemerovo, Russian Federation
* Corresponding author: email@example.com
For the prevention and treatment of gastrointestinal diseases, the microbiome of the living organism is of great importance. The human health depends on quantitative and qualitative composition of microbiota. Under the influence of factors of internal and external environment there is a change in the indigenous microflora. For correction, prevention and regulation of intestinal microbiocenosis within the framework of the biotechnology program, biologically active additive (BAA) is proposed, the main components of which are selective biomass bacteria, prebiotics, peptide ultralisates. As substances that perform the function of coenzymes, thiamine (vitamin B1) and pyridoxine (vitamin B6) are used in the production of this additive. The novelty of the technology is the composition and structure of solid gelatin capsules, ensuring maximum safety of biologically active ingredients and delivery of them to cells. Regulated quality indicators have been established. Sanitary-hygienic and sanitary-toxicological indicators of the BAA comply with the requirements of TR CU 021/2011 “On safety of food products”. Clinical approbation of the developed additive was carried out by volunteers with detected disorders of intestinal microbiota. BAA was taken 1 capsule 2 times a day in conjunction with other drugs regulating bowel biocenosis. At the end of dietary therapy, the microbiota recovery was observed in 90% of cases. Technical documentation has been approved for the new product, recommendations for application have been developed.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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