| Issue |
E3S Web of Conf.
Volume 222, 2020
International Scientific and Practical Conference “Development of the Agro-lndustrial Complex in the Context of Robotization and Digitalization of Production in Russia and Abroad” (DAIC 2020)
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|---|---|---|
| Article Number | 02027 | |
| Number of page(s) | 5 | |
| Section | Modern Directions of Highly Productive Environmentally Friendly Agro- and Water Management, Development and Implementation of Systems for the Rational use of Modern Chemical and Biological Protection of Agricultural Plants and Animals, the Use of New Drugs, Growth Agents, Antidepressants, Immunostimulants, Probiotics and Feed Additives | |
| DOI | https://doi.org/10.1051/e3sconf/202022202027 | |
| Published online | 22 December 2020 | |
Experimental and clinical justification of male orchidectomy under local anesthesia in combination with xylazine and subanesthetic doses of zoletil
1 FSBEI HE “Irkutsk State Agrarian University named after A.A. Ezhevsky”, 664038 Irkutsk, Russia
2 National University of Bioresources and Nature Management of Ukraine, Kiev, Ukraine
* Corresponding author: den120577@bk.ru
The objective of our study was to establish the possibility of safe and painless castration of males using only sedatives together with local anesthesia. Animals, before appropriate fixation, were intramuscularly injected with xylanit (active substance xylazine) at a minimum dose of 1 mg/kg of live weight and zoletil at a subanesthetic dose of 1 mg/kg of animal weight, the testes and scrotal skin were infiltrated with 2% lidocaine solution according to the generally accepted method in veterinary surgery. Before, during, and after surgery, nociception indicators were evaluated: blood pressure; heart rate and respiration rate; degree of pain relief depth (presence of pain and spontaneous movement). During the surgery, the heart rate decreased, on average, by 40-50 beats/minute from baseline values, the respiratory rate decreased, on average, by 10 breaths/minute, and there was a decrease in blood pressure. We found that pre-sedation of animals with xylanite and subanesthetic doses of zoletil followed by tissue infiltration with lidocaine allowed humanely performing orchidectomy, as well as minimizing the cost of general anesthesia and the duration of anesthesia aftereffect on the body.
© The Authors, published by EDP Sciences, 2020
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