| Issue |
E3S Web Conf.
Volume 292, 2021
2021 2nd International Conference on New Energy Technology and Industrial Development (NETID 2021)
|
|
|---|---|---|
| Article Number | 03089 | |
| Number of page(s) | 9 | |
| Section | Environmental Sustainable Development and Industrial Transformation | |
| DOI | https://doi.org/10.1051/e3sconf/202129203089 | |
| Published online | 09 September 2021 | |
Progress in tumor-derived exosome miRNA regulating tumor metastasis research
1 School of Shanxi Medical University, Taiyuan, Shanxi 030001, China ;
2 School of Jilin University, Changchun, Jilin 130012, China ;
† These authors contributed equally.
* Corresponding author: liyq1318@mails.jlu.edu.cn
Tumor metastasis is the most important biological feature of a malignant tumor. It is also a complex process involving multi-step, multi-gene, and multi-products. Tumor cell-derived exosomes are vesicles secreted by tumor cells, containing proteins, lipids, noncoding RNA, and other components. MicroRNA (miRNA) of tumor cell-derived exosomes affects the tumor cell microenvironment and participates in tumor metastasis by activating various signaling pathways. Here, we summarize the miRNA and its related pathways that affect many factors of tumor metastasis and discuss the role of tumor-derived miRNA in the treatment and prevention of tumor metastasis. We also conclude the targets of tumor-derived miRNA in recent years. This article can provide new ideas for the development of tumor metastasis targeting drugs in the future.
© The Authors, published by EDP Sciences, 2021
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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