| Issue |
E3S Web Conf.
Volume 292, 2021
2021 2nd International Conference on New Energy Technology and Industrial Development (NETID 2021)
|
|
|---|---|---|
| Article Number | 03095 | |
| Number of page(s) | 5 | |
| Section | Environmental Sustainable Development and Industrial Transformation | |
| DOI | https://doi.org/10.1051/e3sconf/202129203095 | |
| Published online | 09 September 2021 | |
Smoking Products Suppress Type I IFN During SARS-Cov-2 Infection
Department of Mathematics and Department of Biology, Rensselaer Polytechnic Institute ; Troy, NY, U.S.A.
Coronavirus disease 2019 (COVID-19) is a global pandemic caused by the severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), which can lead to the development severe pneumonia. While some hospital data shows a positive correlation between smoking and severe pneumonia, more molecular-level mechanisms need to be determined. The previous study investigates the mechanism of the negative effect of smoking on anti-viral infection on Type I interferons (IFNs). Research has shown that Type I IFNs play an important role in defending against SARS-Cov-2. Here, we want to investigate smoking components’ effects on SARS-CoV-2 at the molecular level in vitro and give some ideas on the correlation between smoking and syndrome.
© The Authors, published by EDP Sciences, 2021
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