| Issue |
E3S Web of Conf.
Volume 389, 2023
Ural Environmental Science Forum “Sustainable Development of Industrial Region” (UESF-2023)
|
|
|---|---|---|
| Article Number | 07007 | |
| Number of page(s) | 7 | |
| Section | IT in Environmental Science | |
| DOI | https://doi.org/10.1051/e3sconf/202338907007 | |
| Published online | 31 May 2023 | |
Interaction of bacteria with graphene oxide particles reduces their ability to biofilm formation on PVC Microplates
1 MIREA - Russian Technological University, Prospekt Vernadskogo, 78, 119454, Moscow, Russia
2 Orenburg Federal Research Center of Ural Branch of the RAS, Naberezhnaya Street, 29, 460014, Orenburg, Russia
* Corresponding author: zhos-rus@mail.ru
Progress in the diagnosis and treatment of human diseases is impossible without the use of catheters and implants in contact with the skin, mucosal epithelium and blood of the patient. An important task in the manufacture of implantable medical devices is their resistance to protein biofouling and the formation of bacterial biofilm on their surface. The interaction of bacteria with graphene oxide particles contributed to a decrease in the number of Staphylococcus aureus (48.6±1.7% CFU) and Escherichia coli (29.7±2.1% CFU) bacteria. Incubation of Staphylococcus aureus and Escherichia coli cells with graphene oxide particles resulted in a decrease in the ability to biofilm formation on 96-Well Clear PVC Microplates. The creation of composite materials based on polyvinyl chloride and graphene may be one of the strategies for reducing biofilm formation on the surface of implantable medical devices.
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.