| Issue |
E3S Web Conf.
Volume 395, 2023
International Scientific and Practical Conference “Ensuring the Technological Sovereignty of the Agro-Industrial Complex: Approaches, Problems, Solutions” (ETSAIC2023)
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|---|---|---|
| Article Number | 03004 | |
| Number of page(s) | 6 | |
| Section | Creation of Safe and High Quality, Including Functional Food Products Based on Modern Genetic and Selection Methods in Crop and Livestock Production | |
| DOI | https://doi.org/10.1051/e3sconf/202339503004 | |
| Published online | 06 June 2023 | |
Determination of the functional properties of protein hydrolysates by the in silico method
1 South Ural State University (national research university), 454000, Lenin Avenue, 75, Chelyabinsk, Russia
2 Ural State Agrarian University, 620075, Karl Liebknecht street, 42, Ekaterinburg, Russia
* Corresponding author: zinoks-vl@mail.ru
Bioactive peptides are of increasing interest to scientists. The development of peptidomics and bioinformatics contributes to a deeper study of peptides obtained by enzymatic hydrolysis of raw materials. In this work, the in silico method was used to study the properties and biological value of peptides identified in protein hydrolysates obtained by microbial fermentation of the broiler chicken gizzards in whey with the addition of bifidobacteria and propionic acid bacteria. The activity of the peptides was determined using the BIOPEP database. Potential toxicity and such properties as hydrophobicity, hydropathicity, hydrophilicity, molecular weight of each peptide were predicted through the tool ToxinPred. The potential activity of the peptides was evaluated using the PeptideRanker database. The conducted studies made it possible to identify bioactive peptides TR, SY, VW, PPP, SW in hydrolysates, which have various physiological effects. Several peptides with high potential biological activity have also been identified. Due to the fact that not all peptides obtained during the fermentation of raw materials have been studied, in silico methods allow us to assess the feasibility of isolating certain peptides from hydrolysates.
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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