A review of Microfluidic blood separation techniques

¹ Industrial Engineering Department, Faculty of Engineering, Bina Nusantara University, Jakarta, 11480, Indonesia
² Industrial Engineering Department, BINUS Graduate Program - Master of Industrial Engineering, Bina Nusantara University, Jakarta, Indonesia 11480
³ Computer Engineering Department, Faculty of Engineering, Bina Nusantara University, Jakarta, Indonesia 11480

^* Corresponding author: christian.harito@binus.ac.id

Abstract

Microfluidic blood separation is a modern biological technology used to separate blood cells from their fluids. Blood cells present in the blood become an important outline of many diseases. To maintain the stability and sterility of blood, a tool with renewable technology and a large capacity is needed. Microfluidic blood separation has important assets, especially changes in the physicochemical properties of blood cells that are used for quick and accurate clinical diagnosis. Dissemination of structural materials and compositions from the separation and sorting of blood uses a technical system that will create this optimal microfluidic blood separation in research. As for this paper structure starts with introduction, then continued with literature review, type of Microfluidic methods, application of Microfluidic, and bibliometric analysis. With those methods the result could be conducted with systematic literature reviews. Therefore, this study is prepared to identify research gaps in topics related to Microfluidic blood separation techniques. Related studies about microfluidic blood separation techniques are identified using bibliometric analysis and systematic literature review of the study search index through database Scopus-indexed publications. The results from this paper reveal the topics in urine as a parameter for Microfluidic separations as the research gap according to Microfluidic separations. This paper expects research on Microfluidic blood separation techniques will continue to be developed to maximize the potential of Microfluidic blood separations in helping the research process.