Comparative analysis of mammary lump histology and elasto-graphy results at a tertiary hospital

¹ Associate Professor Dept. of General Surgery, Dr. Rajendra Gode Medical College, Amravati
² Professor Dept. of Biochemistry, Dr. Rajendra Gode Medical College, Amravati
³ Tutor Dept. of Biochemistry Dr. Rajendra Gode Medical College, Amravati
⁴ Lecturer Dept. of Pharmacology Dr. Rajendra Gode Institute of Pharmacy, Amravati
⁵ Assistant Professor Dept. of Mechanical Dr. Rajendra Gode Institute of Technology and Research, Amravati
⁶ Associate Professor Dept. of Preventive and Social Medicine Dr. Rajendra Gode Ayurvedic College and Hiospital, Amravati

¹ Corresponding author: libinkahe@gmail.com

Abstract

In the majority of India's metropolitan populations, mammary carcinoma has become the commonest type of carcinoma. A non-invasive imaging method called mammary sono-elasto-graphy can reveal information about mammary lesions. Aims & objectives: In the current research, we examined the diagnostic efficacy of elasto-graphy and histopathological findings of mammary lumps. Material and Methods: The current investigation involved Female patients had solid mammary lesions less than 3 cm in size that were visible on sonography. Classified as BI RADS 3 and 4 lesions, these lesions. Results: 252 female patients had U.S.G. elastography, followed by biopsy or surgery, and histopathology reports were available during the research period. Histopathologically, 104 (41.72%) samples were benign, and the remaining 148 (58.73%) were malignant. Age, B.I.R.A.D.S., Elastography Score, and Strain Ratio were all statistically higher in malignant cases than in benign patients (p 0.001). According to Histo-pathological analysis, fibroadenoma (77.03%) accounted for the majority of benign lesions, followed by Abscess (5.41%), sclerosing adenosis (1.35%), benign fibroepithelial lesion (6.76%), and fibrocystic disease (9.46%). Conversely, poorly differentiated invasive carcinoma (5.77%), invasive ductal carcinoma (67.31%), and invasive mucinous carcinoma (13.46%), IL.C. (5.77%), medullary carcinoma (1.92%), papillary carcinoma (1.92%), and phylloid (1.92%) made up the bulk of malignant cases, Excellent results were noticed with the combination of Ultrasound Score + Elastography Score + Strain Ratio, with scores of 96.00%, 96.05%, 96.03%, 94.12%, and 97.33%, respectively, for susceptibility, accuracy, diagnostic accuracy, and N.P.V. and PPV. Conclusion: The ability to distinguish between benign and malignant mammary masses using ultra-sound elasto-graphy, strain elasto-graphy, and ultra-sound score has good susceptibility, accuracy, and diagnostic accuracy.