| Issue |
E3S Web Conf.
Volume 530, 2024
2024 14th International Conference on Future Environment and Energy (ICFEE 2024)
|
|
|---|---|---|
| Article Number | 02001 | |
| Number of page(s) | 8 | |
| Section | Analysis and Restoration of Aquatic Environment | |
| DOI | https://doi.org/10.1051/e3sconf/202453002001 | |
| Published online | 29 May 2024 | |
Biodegradation of Prazosin by Bacillus sp. Isolated from PPCPs Contaminated River in Malaysia
1 Graduate School of Life and Environmental Sciences, University of Tsukuba 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8572, Japan
2 Department of Environmental Engineering and Green Technology, Malaysia-Japan International Institute of Technology, Univerisiti Teknologi Malaysia, Jalan Sultan Yahya Petra, 54100, Kuala Lumpur, Malaysia
3 Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 113-8657, Tokyo, Japan
* Corresponding author: utsumi.motoo.ge@u.tsukuba.ac.jp
Prazosin (PRZ) is a type of drug used to treat hypertension. It is found to contaminate the aquatic environment, therefore has substantial threats to the ecosystem and human health. PRZ has been found to contaminate rivers in Malaysia which is presumed due to excretion and inappropriate disposal. A tropical bacterium, PR5 has been isolated from a PRZ contaminated site in Kuala Lumpur, Malaysia. It has demonstrated its capabilities to utilize PRZ as a nutrient source and efficiently degrade PRZ. UPLC-TUV is used to measure PRZ concentration during growing cell assay and the results showed that isolate PR5 able to degrade 78% of 0.01 mM PRZ within 7 days of incubation. Species identification based on the 16S rRNA gene sequence showed isolate PR5 has a 99.66% similarity with Bacillus velezensis. This study reports on the first finding of PRZ biodegradation by Bacillus velezensis.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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