| Issue |
E3S Web Conf.
Volume 619, 2025
3rd International Conference on Sustainable Green Energy Technologies (ICSGET 2025)
|
|
|---|---|---|
| Article Number | 04009 | |
| Number of page(s) | 8 | |
| Section | Materials for a Sustainable Future | |
| DOI | https://doi.org/10.1051/e3sconf/202561904009 | |
| Published online | 12 March 2025 | |
Comprehensive Review on Role of Nanoparticles in Gene Therapy
1 Assistant Professor, School of Pharmacy, RK University, Rajkot
2 Assistant Professor, School of Pharmacy, RK University, Rajkot
3 Professor, School of Pharmacy, RK University, Rajkot
4 Assistant Professor, Department of EEE, Vardhaman College of Engineering, Hyderabad, India
* Corresponding author: pratik.vediya@rku.ac.in
Gene therapy is a promising molecular-level treatment for a variety of ailments, including genetic problems. Nanoparticles are essential to the advancement of this treatment. The various roles that nanoparticles play in gene therapy are examined in this abstract, with special attention to their importance in targeted medication administration, increased transfection efficiency, and regulated release of genetic material. Using nanoparticles as carriers for nucleic acids, such as DNA and RNA, is one of the main uses of these particles in gene therapy. Their small size and adaptable surface characteristics allow genetic material to be efficiently encapsulated and protected, allowing for its safe delivery to target cells. The therapeutic efficacy of gene-based therapies is increased and off-target effects are reduced because to this focused delivery. Additionally, by altering their surface to support cellular growth, nanoparticles can get past biological barriers like cell membranes.
Key words: Gene therapy / Nanoparticles / Nucleic acids / Gene based therapy
© The Authors, published by EDP Sciences, 2025
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