“Nanoparticles as Vaccine Heroes: Unveiling Their Impact” – A Review

¹ Assistant Professor, School of Pharmacy, RK University, Rajkot.
² Professor, Vardhaman College of Engineering, Hyderabad, India

^* Corresponding author: ishita.zalavadiya@rku.ac.in

Abstract

Nanoparticles are essential for the advancement of vaccine administration and development because they help create immunisation plans that are more focused, safe, and effective. This abstract delves into the various functions of nanoparticles in vaccines, highlighting how they can boost immunogenicity, stabilise antigens, and enable regulated release. Tailored techniques to treat infectious diseases are made possible by the diverse carriers that nanoparticles, such as liposomes, polymeric nanoparticles, and virus-like particles, provide for antigens, adjuvants, or nucleic acids. These nanoscale platforms enable the co-delivery of several components to elicit strong and durable immune responses in addition to optimising antigen presentation to the immune system. Additionally, their capacity for immune system modification and mucosal administration creates new opportunities for the creation of vaccines against a variety of diseases. By addressing issues including antigen degradation, low immunogenicity, and the requirement for adjuvants, the use of nanotechnology into vaccine design presents a viable avenue to overcoming the present barriers to vaccination efficacy. The use of nanoparticles into vaccines highlights their revolutionary potential to revolutionise preventative medicine and provide novel approaches to address worldwide health issues.