Forging the Future of Nanomedicine: A Comprehensive Review of 3D Printed Suppositories

¹ School of Pharmaceutical Sciences, Atmiya University, Rajkot, Gujarat, India
² School of pharmacy. RK University, Rajkot, Gujarat, India
³ Vardhaman College of Engineering, Hyderabad, India

^* Corresponding author: vaibhavi.savalia@rku.ac.in

Abstract

3D printing (3DP) technology has revolutionized the pharmaceutical industry, offering innovative solutions for the design and production of pharmaceutical dosage forms. Moreover, the integration of 3DP and nanotechnology in the medical field has provided a means to tackle the challenges of producing solid forms for nanomedicines. Within these advancements, research and development on 3DP suppositories has demonstrated considerable potential. This review aims to comprehensively assess the current landscape of 3DP suppositories, with a particular emphasis on their significance, advantages, challenges and future prospects in the pharmaceutical field. The key objective of this article is to highlight the distinct abilities of 3DP in customizing suppositories to cater to individual patient needs, from personalized dosages to controlled drug release profiles. It also explores the benefits of 3DP when compared to traditional manufacturing methods, including improvements in drug solubility, enhanced drug stability, and the creation of intricate suppository shapes. The review addresses challenges associated with regulatory compliance, material selection, and quality control in the context of 3DP suppositories, emphasizing the importance of standardization and quality assurance. In nutshell, this review underscores the significance of 3DP suppositories as a cutting-edge approach to pharmaceutical dosage forms, with the potential to enhance drug effectiveness and patient outcomes.