HTTP_Request2_Exception Unable to connect to tcp://think-ws.ca.edps.org:85. Error: php_network_getaddresses: getaddrinfo failed: Name or service not known A Review of the Role of Gut microbiome in Obesity | E3S Web of Conferences
Open Access
Issue
E3S Web Conf.
Volume 218, 2020
2020 International Symposium on Energy, Environmental Science and Engineering (ISEESE 2020)
Article Number 03010
Number of page(s) 8
Section Environmental Chemistry and Environmental Pollution Analysis and Control
DOI https://doi.org/10.1051/e3sconf/202021803010
Published online 11 December 2020
  1. Villanueva-Millan, M.J., P. Perez-Matute, and J.A. Oteo, Gut microbiota: a key player in health and disease. A review focused on obesity. Journal of Physiology and Biochemistry, 2015. 71(3): p. 509-525. [Google Scholar]
  2. Sender, R., S. Fuchs, and R. Milo, Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans. Cell, 2016. 164(3): p. 337-340. [CrossRef] [PubMed] [Google Scholar]
  3. Zhang, T., et al., Beneficial Effect of Intestinal Fermentation of Natural Polysaccharides. Nutrients, 2018. 10(8). [Google Scholar]
  4. Lee, Y.K. and S.K. Mazmanian, Has the Microbiota Played a Critical Role in the Evolution of the Adaptive Immune System? Science, 2010. 330 (6012): p. 1768-1773. [CrossRef] [Google Scholar]
  5. Mentella, M.C., et al., Nutrition, IBD and Gut Microbiota: A Review. Nutrients, 2020. 12(4). [Google Scholar]
  6. Gurung, M., et al., Role of gut microbiota in type 2 diabetes pathophysiology. Ebiomedicine, 2020. 51. [Google Scholar]
  7. Deng, W., et al., The use of molecular techniques based on ribosomal RNA and DNA for rumen microbial ecosystem studies: a review. Molecular Biology Reports, 2008. 35(2): p. 265-274. [CrossRef] [PubMed] [Google Scholar]
  8. Mardis, E.R., The impact of next-generation sequencing technology on genetics. Trends in Genetics, 2008. 24(3): p. 133-141. [CrossRef] [Google Scholar]
  9. Ley, R.E., et al., Obesity alters gut microbial ecology. Proceedings of the National Academy of Sciences of the United States of America, 2005. 102(31): p. 11070-11075. [Google Scholar]
  10. Backhed, F., et al., The gut microbiota as an environmental factor that regulates fat storage. Proceedings of the National Academy of Sciences of the United States of America, 2004. 101(44): p. 15718-15723. [CrossRef] [PubMed] [Google Scholar]
  11. Ng, M., et al., Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet, 2014. 384 (9945): p. 766-781. [CrossRef] [PubMed] [Google Scholar]
  12. Finkelstein, E.A., et al., Obesity and Severe Obesity Forecasts Through 2030. American Journal of Preventive Medicine, 2012. 42(6): p. 563-570. [CrossRef] [PubMed] [Google Scholar]
  13. Leocadio, P.C.L., et al., Obesity: More Than an Inflammatory, an Infectious Disease? Frontiers in Immunology, 2020. 10. [PubMed] [Google Scholar]
  14. Diaz-Rizzolo, D.A., et al., Healthy dietary pattern and their corresponding gut microbiota profile are linked to a lower risk of type 2 diabetes, independent of the presence of obesity. Clinical Nutrition, 2020. 39(2): p. 524-532. [CrossRef] [Google Scholar]
  15. Ghazizadeh, H., et al., Association between obesity categories with cardiovascular disease and its related risk factors in the MASHAD cohort study population. Journal of Clinical Laboratory Analysis, 2019. [Google Scholar]
  16. Yang, Z., et al., Trends in overweight and obesity by socioeconomic status in Year 6 school children, Australian Capital Territory, 2006-2018. Bmc Public Health, 2019. 19(1). [Google Scholar]
  17. Cortes, V.A., F. Barrera, and F. Nervi, Pathophysiological connections between gallstone disease, insulin resistance, and obesity. Obesity Reviews, 2020. 21(4). [CrossRef] [Google Scholar]
  18. Backhed, F., et al., Host-bacterial mutualism in the human intestine. Science, 2005. 307 (5717): p. 1915-1920. [CrossRef] [PubMed] [Google Scholar]
  19. Kim, B., H.-N. Choi, and J.-E. Yim, Effect of Diet on the Gut Microbiota Associated with Obesity. Journal of obesity & metabolic syndrome, 2019. 28(4): p. 216-224. [CrossRef] [PubMed] [Google Scholar]
  20. Sonnenburg, J.L. and F. Backhed, Diet-microbiota interactions as moderators of human metabolism. Nature, 2016. 535 (7610): p. 56-64. [CrossRef] [PubMed] [Google Scholar]
  21. Dominguez-Bello, M.G., et al., Development of the Human Gastrointestinal Microbiota and Insights From High-Throughput Sequencing. Gastroenterology, 2011. 140(6): p. 1713-1719. [CrossRef] [PubMed] [Google Scholar]
  22. Spor, A., O. Koren, and R. Ley, Unravelling the effects of the environment and host genotype on the gut microbiome. Nature Reviews Microbiology, 2011. 9(4): p. 279-290. [Google Scholar]
  23. Yatsunenko, T., et al., Human gut microbiome viewed across age and geography. Nature, 2012. 486 (7402): p. 222-+. [CrossRef] [PubMed] [Google Scholar]
  24. Carding, S., et al., Dysbiosis of the gut microbiota in disease. Microbial Ecology in Health and Disease, 2015. 26(Suppl. 2): p. 26191-Article No.: 26191. [CrossRef] [PubMed] [Google Scholar]
  25. Turnbaugh, P.J. and J.I. Gordon, The core gut microbiome, energy balance and obesity. Journal of Physiology-London, 2009. 587(17): p. 4153-4158. [CrossRef] [PubMed] [Google Scholar]
  26. Eckburg, P.B., et al., Diversity of the human intestinal microbial flora. Science, 2005. 308 (5728): p. 1635-1638. [CrossRef] [PubMed] [Google Scholar]
  27. Cardinelli, C.S., et al., Influence of Intestinal Microbiota on Body Weight Gain: a Narrative Review of the Literature. Obesity Surgery, 2015. 25(2): p. 346-353. [CrossRef] [PubMed] [Google Scholar]
  28. Macfarlane, S. and G.T. Macfarlane, Regulation of short-chain fatty acid production. Proceedings of the Nutrition Society, 2003. 62(1): p. 67-72. [CrossRef] [Google Scholar]
  29. Kobyliak, N., et al., Probiotics in prevention and treatment of obesity: a critical view. Nutrition & Metabolism, 2016. 13. [PubMed] [Google Scholar]
  30. Tilg, H. and A. Kaser, Gut microbiome, obesity, and metabolic dysfunction. Journal of Clinical Investigation, 2011. 121(6): p. 2126-2132. [CrossRef] [PubMed] [Google Scholar]
  31. Ley, R.E., et al., Microbial ecology Human gut microbes associated with obesity. Nature, 2006. 444 (7122): p. 1022-1023. [CrossRef] [PubMed] [Google Scholar]
  32. Zhang, H., et al., Human gut microbiota in obesity and after gastric bypass. Proceedings of the National Academy of Sciences of the United States of America, 2009. 106(7): p. 2365-2370. [CrossRef] [PubMed] [Google Scholar]
  33. Duncan, S.H., et al., Human colonic microbiota associated with diet, obesity and weight loss. International Journal of Obesity, 2008. 32(11): p. 1720-1724. [CrossRef] [PubMed] [Google Scholar]
  34. Schwiertz, A., et al., Microbiota and SCFA in Lean and Overweight Healthy Subjects. Obesity, 2010. 18(1): p. 190-195. [CrossRef] [PubMed] [Google Scholar]
  35. Collado, M.C., et al., Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women. American Journal of Clinical Nutrition, 2008. 88(4): p. 894-899. [CrossRef] [Google Scholar]
  36. Turnbaugh, P.J., et al., An obesity-associated gut microbiome with increased capacity for energy harvest. Nature, 2006. 444 (7122): p. 1027-1031. [CrossRef] [PubMed] [Google Scholar]
  37. Santacruz, A., et al., Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women. British Journal of Nutrition, 2010. 104(1): p. 83-92. [CrossRef] [Google Scholar]
  38. Liu, R., et al., Gut microbiome and serum metabolome alterations in obesity and after weightloss intervention. Nature Medicine, 2017. 23(7): p. 859-+. [CrossRef] [PubMed] [Google Scholar]
  39. Armougom, F., et al., Monitoring Bacterial Community of Human Gut Microbiota Reveals an Increase in Lactobacillus in Obese Patients and Methanogens in Anorexic Patients. Plos One, 2009. 4(9). [Google Scholar]
  40. Balamurugan, R., et al., Quantitative differences in intestinal Faecalibacterium prausnitzii in obese Indian children. British Journal of Nutrition, 2010. 103(3): p. 335-338. [CrossRef] [Google Scholar]
  41. Galley, J.D., et al., Maternal Obesity Is Associated with Alterations in the Gut Microbiome in Toddlers. Plos One, 2014. 9(11). [Google Scholar]
  42. Kalliomaki, M., et al., Early differences in fecal microbiota composition in children may predict overweight. American Journal of Clinical Nutrition, 2008. 87(3): p. 534-538. [CrossRef] [Google Scholar]
  43. Turnbaugh, P.J., et al., Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host & Microbe, 2008. 3(4): p. 213-223. [CrossRef] [PubMed] [Google Scholar]
  44. Turnbaugh, P.J., et al., The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice. Science Translational Medicine, 2009. 1(6). [Google Scholar]
  45. Jumpertz, R., et al., Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. American Journal of Clinical Nutrition, 2011. 94(1): p. 58-65. [CrossRef] [Google Scholar]
  46. Koo, S.H., et al., A pilot study to examine the association between human gut microbiota and the host’s central obesity. JGH open : an open access journal of gastroenterology and hepatology, 2019. 3(6): p. 480-487. [PubMed] [Google Scholar]
  47. Hildebrandt, M.A., et al., High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity. Gastroenterology, 2009. 137(5): p. 1716-1724. [CrossRef] [PubMed] [Google Scholar]
  48. Nadal, I., et al., Shifts in clostridia, bacteroides and immunoglobulin-coating fecal bacteria associated with weight loss in obese adolescents. International Journal of Obesity, 2009. 33(7): p. 758-767. [CrossRef] [PubMed] [Google Scholar]
  49. Roediger, W.E., Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut, 1980. 21(9): p. 793-8. [CrossRef] [PubMed] [Google Scholar]
  50. Nagpal, R., et al., Gut Microbiome Composition in Non-human Primates Consuming a Western or Mediterranean Diet. Frontiers in Nutrition, 2018. 5. [PubMed] [Google Scholar]
  51. Liu, B., et al., Western diet feeding influences gut microbiota profiles in apoE knockout mice. Lipids in Health and Disease, 2018. 17. [PubMed] [Google Scholar]
  52. Villamil, S.I., et al., Adverse effect of early-life highfat/high-carbohydrate (“Western”) diet on bacterial community in the distal bowel of mice. Nutrition Research, 2018. 50: p. 25-36. [CrossRef] [Google Scholar]
  53. Meslier, V., et al., Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake. Gut, 2020. [Google Scholar]
  54. Garcia-Mantrana, I., et al., Shifts on Gut Microbiota Associated to Mediterranean Diet Adherence and Specific Dietary Intakes on General Adult Population. Frontiers in Microbiology, 2018. 9. [PubMed] [Google Scholar]
  55. De Filippo, C., et al., Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proceedings of the National Academy of Sciences of the United States of America, 2010. 107(33): p. 14691-14696. [CrossRef] [PubMed] [Google Scholar]
  56. Zimmer, J., et al., A vegan or vegetarian diet substantially alters the human colonic faecal microbiota. European Journal of Clinical Nutrition, 2012. 66(1): p. 53-60. [CrossRef] [PubMed] [Google Scholar]
  57. Jeffery, I.B. and P.W. O’Toole, Diet-Microbiota Interactions and Their Implications for Healthy Living. Nutrients, 2013. 5(1): p. 234-252. [CrossRef] [PubMed] [Google Scholar]
  58. Martens, E.C., et al., The Devil Lies in the Details: How Variations in Polysaccharide Fine-Structure Impact the Physiology and Evolution of Gut Microbes. Journal of Molecular Biology, 2014. 426(23): p. 3851-3865. [CrossRef] [PubMed] [Google Scholar]
  59. Topping, D.L. and P.M. Clifton, Short-chain fatty acids and human colonic function: Roles of resistant starch and nonstarch polysaccharides. Physiological Reviews, 2001. 81(3): p. 1031-1064. [CrossRef] [PubMed] [Google Scholar]
  60. Cook, S.I. and J.H. Sellin, Review article: short chain fatty acids in health and disease. Alimentary Pharmacology & Therapeutics, 1998. 12(6): p. 499-507. [CrossRef] [PubMed] [Google Scholar]
  61. de la Cuesta-Zuluaga, J., et al., Higher Fecal Short Chain Fatty Acid Levels Are Associated with Gut Microbiome Dysbiosis, Obesity, Hypertension and Cardiometabolic Disease Risk Factors. Nutrients, 2019. 11(1). [Google Scholar]
  62. McNeil, N.I., The contribution of the large intestine to energy supplies in man. The American journal of clinical nutrition, 1984. 39(2): p. 338-42. [CrossRef] [PubMed] [Google Scholar]
  63. Flint, H.J., et al., Microbial degradation of complex carbohydrates in the gut. Gut Microbes, 2012. 3(4): p. 289-306. [CrossRef] [Google Scholar]
  64. Walker, A.W., et al., pH and peptide supply can radically alter bacterial populations and short-chain fatty acid ratios within microbial communities from the human colon. Applied and Environmental Microbiology, 2005. 71(7): p. 3692-3700. [CrossRef] [PubMed] [Google Scholar]
  65. den Besten, G., et al., The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. Journal of Lipid Research, 2013. 54(9): p. 2325-2340. [CrossRef] [PubMed] [Google Scholar]
  66. Hong, Y.H., et al., Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43. Endocrinology, 2005. 146(12): p. 5092-5099. [CrossRef] [PubMed] [Google Scholar]
  67. Gao, Z., et al., Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice. Diabetes, 2009. 58(7): p. 1509-1517. [CrossRef] [PubMed] [Google Scholar]
  68. Brown, A.J., et al., The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. Journal of Biological Chemistry, 2003. 278(13): p. 11312-11319. [CrossRef] [PubMed] [Google Scholar]
  69. Byrne, C.S., et al., The role of short chain fatty acids in appetite regulation and energy homeostasis. International Journal of Obesity, 2015. 39(9): p. 1331-1338. [CrossRef] [PubMed] [Google Scholar]
  70. Fernandes, J., et al., Adiposity, gut microbiota and faecal short chain fatty acids are linked in adult humans. Nutrition & Diabetes, 2014. 4. [Google Scholar]
  71. Riva, A., et al., Pediatric obesity is associated with an altered gut microbiota and discordant shifts in Firmicutes populations. Environmental Microbiology, 2017. 19(1): p. 95-105. [CrossRef] [PubMed] [Google Scholar]
  72. Barczynska, R., et al., Bacterial Microbiota and Fatty Acids in the Faeces of Overweight and Obese Children. Polish Journal of Microbiology, 2018. 67(3): p. 339-345. [CrossRef] [PubMed] [Google Scholar]
  73. Backhed, F., et al., Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proceedings of the National Academy of Sciences of the United States of America, 2007. 104(3): p. 979-984. [CrossRef] [PubMed] [Google Scholar]
  74. Winder, W.W. and D.G. Hardie, AMP-activated protein kinase, a metabolic master switch: possible roles in Type 2 diabetes. American Journal of Physiology-Endocrinology and Metabolism, 1999. 277(1): p. E1-E10. [CrossRef] [Google Scholar]
  75. Boulange, C.L., et al., Impact of the gut microbiota on inflammation, obesity, and metabolic disease. Genome Medicine, 2016. 8. [PubMed] [Google Scholar]
  76. Parseus, A., et al., Microbiota-induced obesity requires farnesoid X receptor. Gut, 2017. 66(3): p. 429-437. [CrossRef] [PubMed] [Google Scholar]
  77. Thomas, C., et al., TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis. Cell Metabolism, 2009. 10(3): p. 167-177. [CrossRef] [PubMed] [Google Scholar]
  78. Dumas, M.-E., et al., Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice. Proceedings of the National Academy of Sciences of the United States of America, 2006. 103(33): p. 12511-12516. [CrossRef] [PubMed] [Google Scholar]

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