| Issue |
E3S Web Conf.
Volume 271, 2021
2021 2nd International Academic Conference on Energy Conservation, Environmental Protection and Energy Science (ICEPE 2021)
|
|
|---|---|---|
| Article Number | 04043 | |
| Number of page(s) | 6 | |
| Section | Environmental Materials and Solid Waste Recycling Technology | |
| DOI | https://doi.org/10.1051/e3sconf/202127104043 | |
| Published online | 15 June 2021 | |
Current Development of the Applications of Polymers in Gene Delivery
Department of Chemistry, Virginia Tech, Blacksburg, 24061, Virginia, US
Gene delivery is one of the most important and efficient therapy methods for treating diseases, especially genetic diseases that challenge conventional treatment methods. However, to be efficient, gene delivery has a few requirements for the polymers to be applicable, including the reduction of cytotoxicity, the improvement of transfection efficiency, and the elimination of off-target effects. In this study, the common polymers applied in gene delivery is discussed in depth, regarding such requirements, as well as some of the limitations and potential improvements in gene delivery.
© The Authors, published by EDP Sciences, 2021
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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