E3S Web Conf.
Volume 161, 2020International Conference on Efficient Production and Processing (ICEPP-2020)
|Number of page(s)||4|
|Published online||15 April 2020|
The development of a biologically active additive to reduce the blood cholesterol level
East Siberia State University of Technology and Management (ESSUTM).40V Klyuchevskaya str., Republic of Buryatia, Ulan-Ude, 670013, Russia
* Corresponding author: Ikhamagaeva@mail.ru
The relationship between the content of polyunsaturated fatty acids (PUFAs) of flaxseed oil and the cholesterol-metabolizing activity of various strains of bifidobacteria was studied. The optimum dose of linseed oil in a nutrient medium for the cultivation of bifidobacteria was selected to provide high cholesterol destruction compared to the control. Of all the studied strains of bifidobacteria, the most pronounced destructive activity against cholesterol is displayed by the strain Bifidobacterium longum DK-100, which, with the biomass growth in a nutrient medium of linseed oil destroys 74% of the total cholesterol. When studying the fatty acid composition of the biomass of bifidobacteria, the oleic acid was found to predominate among monounsaturated fatty acids, and the α-linolenic acid to prevail among polyunsaturated fatty acids, that amounted to 44-45%. A decrease in the content of linolenic acid during the cultivation of bifidobacteria was noted, which is probably due to their participation of bifidobacteria in the metabolism. As a result of the studies, the optimum conditions for the cultivation of bifidobacteria were selected and the technological parameters of producing dietary supplements were justified.
© The Authors, published by EDP Sciences, 2020
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