Acute and subacute toxicity study of the methanolic extract of olea europea.L leaves in Wistar rat

Ibrahim Hinad; Youssef S’hih; Radia El Gui; Aboubaker Elhessni; Abdelhalim Mesfioui; Moulay laarbi Ouahidi

doi:10.1051/e3sconf/202131901094

All issues

Volume 319 (2021)

E3S Web Conf., 319 (2021) 01094

References

Open Access

Issue		E3S Web Conf. Volume 319, 2021 International Congress on Health Vigilance (VIGISAN 2021)


Article Number		01094
Number of page(s)		7
DOI		https://doi.org/10.1051/e3sconf/202131901094
Published online		09 November 2021

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[1] S. Chen et al., “A renaissance in herbal medicine identification: From morphology to DNA,” Biotech Adv, vol. 32, no. 7, pp. 1237–1244, Nov. 2014, doi: 10.1016/j.biotechadv.2014.07.004. [Google Scholar]

[2] A. Altemimi, N. Lakhssassi, A. Baharlouei, D. Watson, and D. Lightfoot, “Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts,” Plants, vol. 6, no. 4, p. 42, Sep. 2017, doi: 10.3390/plants6040042. [Google Scholar]

[3] T. Alelign, “Evaluation of Acute and Sub-acute Toxicity of Selected Traditional Antiurolithiatic Medicinal Plant Extracts in Wistar Albino Rats,” p. 29. [Google Scholar]

[4] H. B. Sharif, M. D. Mukhtar, Y. Mustapha, G. Baba, and A. O. Lawal, “Acute and Subchronic Toxicity Profile of Euphorbia pulcherrima Methanol Extract on Wistar Albino Rats,” Adv in Pharmac, vol. 2015, pp. 1–9, Feb. 2015, doi: 10.1155/2015/539646. [Google Scholar]

[5] J. -W. Bae, D. -H. Kim, W. -W. Lee, H. -Y. Kim, and C. -G. Son, “Characterizing the human equivalent dose of herbal medicines in animal toxicity studies,” J of Ethnophar, vol. 162, pp. 1–6, Mar. 2015, doi: 10.1016/j.jep.2014.12.023. [Google Scholar]

[6] L. Di Donna et al., “Secondary metabolites of Olea europaea leaves as markers for the discrimination of cultivars and cultivation zones by multivariate analysis,” Food Chemistry, vol. 121, no. 2, pp. 492–496, Jul. 2010, doi: 10.1016/j.foodchem.2009.12.070. [Google Scholar]

[7] M. Cheurfa, H. H. Abdallah, R. Allem, A. Noui, C. M. N. Picot-Allain, and F. Mahomoodally, “Hypocholesterolaemic and antioxidant properties of Olea europaea L. leaves from Chlef province, Algeria using in vitro, in vivo and in silico approaches,” Food and Chem Toxic, vol. 123, pp. 98–105, Jan. 2019, doi: 10.1016/j.fct.2018.10.002. [Google Scholar]

[8] C. G. Guex, F. Z. Reginato, P. R. de Jesus, J. C. Brondani, G. H. H. Lopes, and L. de F. Bauermann, “Antidiabetic effects of Olea europaea L. leaves in diabetic rats induced by high-fat diet and low-dose streptozotocin,” J of Ethnopharm, vol. 235, pp. 1–7, May 2019, doi: 10.1016/j.jep.2019.02.001. [Google Scholar]

[9] Y. Liu, L. C. McKeever, and N. S. A. Malik, “Assessment of the Antimicrobial Activity of Olive Leaf Extract Against Foodborne Bacterial Pathogens,” Front. Microbiol. , vol. 8, Feb. 2017, doi: 10.3389/fmicb.2017.00113. [Google Scholar]

[10] S. Bulotta et al., “Antioxidant and antigrowth action of peracetylated oleuropein in thyroid cancer cells,” J of Mole Endocr, vol. 51, no. 1, pp. 181–189, Aug. 2013, doi: 10.1530/JME-12-0241. [Google Scholar]

[11] T. Vezza et al., “Immunomodulatory properties of Olea europaea leaf extract in intestinal inflammation,” Mol Nutr & Food Res, vol. 61, no. 10, p. 1601066, 2017, doi: https://doi.org/10.1002/mnfr.201601066. [Google Scholar]

[12] M. Barkaoui, A. Katiri, H. Boubaker, and F. Msanda, “Ethnobotanical survey of medicinal plants used in the traditional treatment of diabetes in Chtouka Ait Baha and Tiznit (Western Anti-Atlas), Morocco,” Jourl of Ethnophar, vol. 198, pp. 338–350, Feb. 2017, doi: 10.1016/j.jep.2017.01.023. [Google Scholar]

[13] H. N. Mrabti et al., “Integrative herbal treatments of diabetes in Beni Mellal region of Morocco,” J of Integr Med, vol. 17, no. 2, pp. 93–99, Mar. 2019, doi: 10.1016/j.joim.2019.01.001. [Google Scholar]

[14] R. Jia et al., “Acute and subchronic toxicity as well as evaluation of safety pharmacology of modified pulsatilla granules,” J of Int Agr, vol. 16, no. 3, pp. 671–678, Mar. 2017, doi: 10.1016/S2095-3119(16)61401-6. [Google Scholar]

[15] N. Acar-Tek and D. Ağagündüz, “Olive Leaf (Olea europaea L. folium): Potential Effects on Glycemia and Lipidemia,” Ann Nutr Metab, vol. 76, no. 1, pp. 10–15, 2020, doi: 10.1159/000505508. [Google Scholar]

[16] I. Hassen, H. Casabianca, and K. Hosni, “Biological activities of the natural antioxidant oleuropein: Exceeding the expectation – A mini-review,” J of Fun Foods, vol. 18, pp. 926–940, Oct. 2015, doi: 10.1016/j.jff.2014.09.001. [Google Scholar]

[17] S. N. El and S. Karakaya, “Olive tree ( Olea europaea ) leaves: potential beneficial effects on human health,” Nutrition Reviews, vol. 67, no. 11, pp. 632–638, Nov. 2009, doi: 10.1111/j.1753-4887.2009.00248.x. [Google Scholar]

[18] C. G. Guex et al., “Safety assessment of ethanolic extract of Olea europaea L. leaves after acute and subacute administration to Wistar rats,” Reg Toxic and Phar, vol. 95, pp. 395–399, Jun. 2018, doi: 10.1016/j.yrtph.2018.04.013. [Google Scholar]

[19] J. E. Hilaly, Z. H. Israili, and B. Lyoussi, “Acute and chronic toxicological studies of Ajuga iva in experimental animals,” J of Ethn, vol. 91, no. 1, pp. 43–50, Mar. 2004, doi: 10.1016/j.jep.2003.11.009. [Google Scholar]

[20] A. omar Sawsan et al., “Toxicity of olive leaves (olea europea) in Wstar Albino rats,” As J of An and Veter Adv, 2012. [Google Scholar]

[21] H. Rhiouani, J. El-Hilaly, Z. H. Israili, and B. Lyoussi, “Acute and sub-chronic toxicity of an aqueous extract of the leaves of Herniaria glabra in rodents,” J of Eth, vol. 118, no. 3, pp. 378–386, Aug. 2008, doi: 10.1016/j.jep.2008.05.009. [Google Scholar]

[22] M. A. Perazella, “Toxic Nephropathies: Core Curriculum 2010,” Am J of Kid Dis, vol. 55, no. 2, pp. 399–409, Feb. 2010, doi: 10.1053/j.ajkd.2009.10.046. [Google Scholar]

[23] T. Y. Faremi, S. M. Suru, M. A. Fafunso, and U. E. Obioha, “Hepatoprotective potentials of Phyllanthus amarus against ethanol-induced oxidative stress in rats,” Food and Chem Tox, vol. 46, no. 8, pp. 2658–2664, Aug. 2008, doi: 10.1016/j.fct.2008.04.022. [Google Scholar]

[24] M. Shahjahan, K. E. Sabitha, M. Jainu, and C. S. S. Devi, “Effect of Solanum trilobatum against carbon tetrachloride induced hepatic damage in albino rats,” p. 6. [Google Scholar]