| Issue |
E3S Web Conf.
Volume 147, 2020
The 3rd International Symposium on Marine and Fisheries Research (3rd ISMFR)
|
|
|---|---|---|
| Article Number | 03008 | |
| Number of page(s) | 6 | |
| Section | Fish Processing Technology | |
| DOI | https://doi.org/10.1051/e3sconf/202014703008 | |
| Published online | 10 February 2020 | |
Production of Unsaturated Fatty Acids Concentrate Tablets from Sardinella sp. Oil
Research and Development Center for Marine and Fisheries Product Processing and Biotechnology Jalan KS. Tubun Petamburan VI, Jakarta Pusat 10260 Indonesia Phone (021) 53650157-53650158, Fax. (021) 53650158
* Corresponding author: rnurbayasari@gmail.com
Tablets are medicinal ingredients in solid dosage forms which are usually prepared with suitable pharmaceutical ingredients. In this study, unsaturated fatty acids concentrate from Sardinella sp. oil was used as raw material and then it was microencapsulated. The microcapsule was formulated into a tablet with proportion of 250 mg concentrated unsaturated fatty acids for each 450 mg tablet. Tablet granules were analyzed for compressibility, flow rate, and fixed angle. While, the tablets were determined for weight uniformity, released time, hardness, and tablet size uniformity. The results showed that compressibility, flow rate and fixed angle of the tablet granules were 5.6%; 10.36 g/sec; and 32.4° respectively. Tablets had 447.85 mg weight uniformity; 48’12” released time; and 0.775 kg hardness. In addition, the tablet size uniformity with diameter 10 mm and thickness 4 mm was 2.5. Based on the pharmacopoeia, the tablets of unsaturated fatty acids concentrate from Sardinella sp. oil had met these requirements, but optimization was still needed for improving the released time and hardness of the tablet.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.