Open Access
Issue
E3S Web Conf.
Volume 308, 2021
2021 6th International Conference on Materials Science, Energy Technology and Environmental Engineering (MSETEE 2021)
Article Number 02012
Number of page(s) 7
Section Environmental Ecology and Biochemical Testing
DOI https://doi.org/10.1051/e3sconf/202130802012
Published online 27 September 2021
  1. Alzheimer’s Disease International, (2019). World Alzheimer Report 2019. https://www.alzint.org/resource/world-alzheimer-report-2019/. [Google Scholar]
  2. Nam, E., Nam, G., Lim M.H. (2019) Synaptic copper, amyloid-β, and neurotransmitters in Alzheimer’s disease. [Google Scholar]
  3. Shibin, M., Senthil, V., Saravanan, S., Diraviyam, T., Balamurugan P. (2020) Role of Tau in Alzheimer’s disease: The prime pathological player. International Journal of Biological Macromolecules, 63, 1599-1617. [Google Scholar]
  4. Zhou H. (2018) Study on the pathogenesis and prevention of Alzheimer’s Disease. Ph D. Thesis, Suzhou University, China. [Google Scholar]
  5. Kardos, J., Kovács, I., Hajós, F., et al. (1989) Nerve endings from rat brain tissue release copper upon depolarization. A possible role in regulating neuronal excitability. Neuroscience letters, 103(2): 139-144. [CrossRef] [PubMed] [Google Scholar]
  6. da Silva G.F.Z., Ming L.J. (2007) Metallo-ROS in Alzheimer’s Disease: Oxidation of Neurotransmitters by CuII -β -Amyloid and Neuropathology of the Disease. Angewandte Chemie International Edition, 46(18): 3337-3341. [Google Scholar]
  7. Cleveland, D.W, Hwo, S.Y, Kirschner M.W. (1977) Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. Journal of molecular biology, 116(2): 207-225. [CrossRef] [PubMed] [Google Scholar]
  8. Das, BC., Pradhan, S., Ojha D.P., Das, A., Hosmane N.S., et al. (2018) The Role of Tau Protein in Diseases. Ann Adv Chem, 2: 001-016. [Google Scholar]
  9. Lee H.G., Perry, G., Moreira P.I., et al. (2005) Tau phosphorylation in Alzheimer’s disease: pathogen or protector?. Trends in Molecular Medicine, 11(4): 164-169. [CrossRef] [PubMed] [Google Scholar]
  10. Reddy P.H. (2017) A critical assessment of research on neurotransmitters in Alzheimer’s disease. Journal of Alzheimer’s Disease, 57(4): 969-974. [Google Scholar]
  11. Mohandas, E., Rajmohan, V., Raghunath, B. (2009) Neurobiology of Alzheimer’s disease. Indian journal of psychiatry, 51(1): 55. [CrossRef] [PubMed] [Google Scholar]
  12. Soreq, H. (2015) Checks and balances on cholinergic signaling in brain and body function. Trends in neurosciences, 38(7): 448-458. [CrossRef] [PubMed] [Google Scholar]
  13. Sun, Z., Zhu, J., Meng, J., Zuo, C., Han Y., Li, P., Sha, J., Fan, Q. (2017) Study About Brain Neurotransmitter Changes in Patients with Alzheimer’s Disease. Medical Innovation of China, 14(14): 9-12. [Google Scholar]
  14. Rajmohan, R., Reddy P.H. (2017) Amyloid-beta and phosphorylated tau accumulations cause abnormalities at synapses of Alzheimer’s disease neurons. Journal of Alzheimer’s Disease, 57(4): 975-999. [Google Scholar]
  15. Bai, X., Zhuang, S., Zhang, G. (2013) Research progress of Aβ protein on Alzheimer’s disease and drug. The Journal of Medical Theory and practice, 26(19): 2552-2553. [Google Scholar]
  16. Eric, R., et al. (2016) Phase 3 solanezumab trials: Secondary outcomes in mild Alzheimer’s disease patients. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 12(2): 110-120. [Google Scholar]
  17. Liang, Z., Fang, L., Li, H., Liu, J., Tan, Q., Long, S., Xu, G. (2018) Current situation and new progress of drug treatment for Alzheimer’s disease. Medical Journal of National Defending Forces in Southwest China, 28(01): 85-87. [Google Scholar]
  18. Farlow, M R., Andreasen, N., Riviere M, et al. (2015) Long-term treatment with active Aβ immunotherapy with CAD106 in mild Alzheimer’s disease. Alzheimer’s Research & Therapy, 7(1):1-13. [Google Scholar]
  19. Theunis, C., Crespo-Biel, N., Gafner, V., et al. Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau. P301L mice that model tauopathy. PLoS One, 8(8): e72301. [Google Scholar]
  20. Panza, F., Solfrizzi, V., Seripa, D., et al. (2016) Tau-based therapeutics for Alzheimer’s disease: active and passive immunotherapy. Immunotherapy, 8(9): 1119-1134. [CrossRef] [PubMed] [Google Scholar]
  21. Lovestone, S., Boada, M., Dubois, B., et al. (2015) A phase II trial of tideglusib in Alzheimer’s disease. Journal of Alzheimer’s Disease, 2015(45): 75-88. [Google Scholar]
  22. Gauthier, S., Feldman, H H., Schneider, L S., et al. (2016) Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer’s disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial. Lancet, 388(10062): 2873-2884. [CrossRef] [PubMed] [Google Scholar]
  23. Li, R. (2013) Current research status of Alzheimer’s disease. Journal of Shenyang Medical College, 15(03): 129-133. [Google Scholar]
  24. Cheng, P., Li, T. (2018) Research progress of acetylcholinesterase inhibitors in the treatment of Alzheimer’disease. Science and technology innovation 018(09): 50-51. [Google Scholar]
  25. Wang, K., Liu W., (2019) Sang Z. Progress of multi-target diease. Chin Pharm J, 54(5): 352-359. [Google Scholar]
  26. Wang, Q., Lv, J., Hu, Y., Liu, L. (2020) Pathogenesis and New Therapeutic Drugs of Alzheimer Disease. Chinese Pharmaceutical Journal, 55(23): 1939-1947. [Google Scholar]
  27. Zhang, J., Wang, R. (2014) Research progress in the pathogenesis of Alzheimer ’ s disease. Journal of Capital Medical University, 35(06): 721-724. [Google Scholar]
  28. de la Monte S.M., Wands J.R. (2005) Review of insulin and insulin-like growth factor expression signaling and malfunction in the central nervous system. J Alzheimers Dis, 7(1): 45-61. [CrossRef] [PubMed] [Google Scholar]
  29. Zhang, W., Liu, H., Zhang, Y., Wang, M. (2021) Research Progresses on Mechanisms of Inflammation in Alzheimer ’ s Disease. Life Science Research, 25(02): 144-150. [Google Scholar]
  30. Yang, R., Zhang, N. (2015) Research Progress on the mechanism of curcumin on Alzheimer’s disease. Journal of Southeast University, 34(1): 152-155. [Google Scholar]
  31. Liang, Y., Cao, G., Zhang, W. (2017) Research progress on inflammation of Alzheimer’s disease and intervention of traditional Chinese medicine. Chinese Pharmacological Bulletin, 35(5): 597-602. [Google Scholar]
  32. Duan, L., Si, J., Liu, P., (2015) Research progress in medication of Alzheimer’s disease. Hebei Medical Journal, 37(07): 1077-1080. [Google Scholar]
  33. Philippidis, A. (2014) Gene therapy briefs. Hum Gene Ther, 25(7): 570-572. [CrossRef] [PubMed] [Google Scholar]
  34. Matsumoto, Y., Niimi, N., Kohyama, K. (2013) Development of a new DNA vaccine for Alzheimer disease targeting a wide range of aβ species and amyloidogenic peptides. PLoS One, 8(9): e75203. [CrossRef] [PubMed] [Google Scholar]
  35. Ben Menachem-Zidon, O., Ben-Menahem, Y., Ben Hur, T., et al. (2015) Intra-hippocampal transplantation of neural precursor cells with transgenic over-expression of LF-1 receptor antagonist rescues memory and neurogenesis impairments in an Alzheimer’s disease model. Neuropsychopharmacology, 39(2): 401-404. [Google Scholar]
  36. Wu, S., Sasaki, A., Yoshimoto, R., et al. (2018) Neural stem cells improve learning and memory in rats with Alzheimer’s disease[J]. Pathobiology, 75(3): 186-194. [Google Scholar]
  37. Li, J., Li, W., Zhou, J. (2015) Gene therapy and Alzheimer’s disease. J Cent South Univ (Med Sci), 40(04): 428-432. [Google Scholar]
  38. Zhu, Q., Xu, Y., Liu, Z. (2016) Research progress of neural stem cells in the treatment of Alzheimer’s disease. Chongqing Medicine, 2016, 45(30): 4286-4288. [Google Scholar]
  39. Cheng, X., Luo, H. (2011) Research progress in Alzheimer’s disease treated by the transplantation of stem cells. Basic & Clinical Medicine, 31(02): 218-221. [Google Scholar]
  40. Baron, R., Nemirovsky, A., Harpaz, I., et al. (2008) IFN-gamma enhances neurogenesis in wild-type mice and in a mouse model of Alzheimer’s disease. FASEB J, 22(8): 2843-2852. [CrossRef] [PubMed] [Google Scholar]
  41. Chen, S., Cai, Q., Shen, Y., et al. (2014) Neural Stem Cell Transplantation Improves Spatial Learning and Memory via Neuronal Regeneration in Amyloid-β Precursor Protein/presenilin 1/tau Triple Transgenic Mice. American Journal of Alzheimer’s Disease & Other Dementias, 29(2):142-149. [Google Scholar]
  42. Lee, J., Jin H., Bae J., (2009) Bone marrow-derived mesenchymal stem cells reduce brain amyloid-beta deposition and accelerate the activation of microglia in an acutely induced Alzheimer’s disease mouse model. Neuroscience letters, 450(2): 136-141. [CrossRef] [PubMed] [Google Scholar]
  43. Liao, B., Li, Y., Tang, N., et al. (2017) Evaluation and Study of the Effect of Repetitive Transcranial Magnetic Stimulation in Treatment of Mental and Behavioral Symptoms of Alzheimer Disease. Medical Innovation of China, 14(34): 21-24. [Google Scholar]
  44. Yu, X., Zhang, Y. (2020) Advances on the treatment of Alzheimer’s disease with deep brain stimulation. Journal of Shangdong University (Health Science), 58(08): 22-27+33. [Google Scholar]
  45. Qian, Y., Shao, Y., Lu, S., Wang, J., Chen, Z. (2019) Research Progress on Traditional Chinese Medicine in the Treatment of Alzheimer’s Disease. Journal of Nanjing University of Chinese Medicine, 35(06): 761-766. [Google Scholar]

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